Factors associated with HIV prevalence in a pre-partum cohort of Zambian women

J. S. St Lawrence, W. Klaskala, C. Kankasa, J. T. West, Charles D Mitchell, C. Wood

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

An ongoing study of mother-to-child human herpes virus-8 (HHV-8) transmission in Zambian women (n=3160) allowed us to examine the association of medical injections with HIV serostatus while simultaneously accounting for other factors known to be correlated with HIV prevalence. Multi-method data collection included structured interviews, medical record abstraction, clinical examinations, and biological measures. Medically administered intramuscular or intravenous injections in the past five years (but not blood transfusions) were overwhelmingly correlated with HIV prevalence, exceeding the contribution of sexual behaviours in a multivariable logistic regression. Statistically significant associations with HIV also were found for some demographic variables, sexual behaviours, alcohol use, and sexually transmitted diseases (STD). The results confirmed that iatrogenic needle exposure, sexual behaviour, demographic factors, substance use, and STD history are all implicated in Zambian women's HIV + status. However, the disproportionate association of medical injection history with HIV highlights the need to investigate further and prospectively the role of health-care injection in sub-Saharan Africa's HIV epidemic.

Original languageEnglish
Pages (from-to)607-613
Number of pages7
JournalInternational Journal of STD and AIDS
Volume17
Issue number9
DOIs
StatePublished - Sep 12 2006

Fingerprint

HIV
Sexual Behavior
Sexually Transmitted Diseases
Injections
Demography
Women's Rights
Africa South of the Sahara
Intramuscular Injections
Intravenous Injections
Blood Transfusion
Needles
Medical Records
Logistic Models
History
Alcohols
Mothers
Interviews
Viruses
Delivery of Health Care

Keywords

  • Association with HIV prevalence
  • Medical injections and HIV
  • Zambian women and HIV

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Immunology

Cite this

Factors associated with HIV prevalence in a pre-partum cohort of Zambian women. / St Lawrence, J. S.; Klaskala, W.; Kankasa, C.; West, J. T.; Mitchell, Charles D; Wood, C.

In: International Journal of STD and AIDS, Vol. 17, No. 9, 12.09.2006, p. 607-613.

Research output: Contribution to journalArticle

St Lawrence, J. S. ; Klaskala, W. ; Kankasa, C. ; West, J. T. ; Mitchell, Charles D ; Wood, C. / Factors associated with HIV prevalence in a pre-partum cohort of Zambian women. In: International Journal of STD and AIDS. 2006 ; Vol. 17, No. 9. pp. 607-613.
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