Extranodal lymphoplasmacytoid lymphoma (immunocytoma) presenting as small intestinal obstruction

A case report and review of the literature

Monica A. Recine, Maria T. Perez, Beria Cabello-Inchausti, Rogerio C. Lilenbaum, Morton J. Robinson

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 57-year-old woman presented with intermittent symptoms of intestinal obstruction. Workup provided nondiagnostic radiologic studies. An exploratory laparotomy revealed a segmental dilatation in the proximal ileum, which showed diffuse thickening of the intestinal wall. Microscopic examination of the affected area disclosed a diffuse transmural infiltrate composed of small lymphocytes, mature plasma cells, and lymphoplasmacytoid cells in different stages of maturation associated with extracellular periodic acid-Schiff-positive material. In addition, serum protein electrophoresis showed a monoclonal immunoglobulin M κ paraprotein. Postoperative workup did not demonstrate evidence of systemic involvement. The morphologic features and immunohistochemical and molecular analyses were consistent with lymphoplasmacytoid lymphoma (immunocytoma). We report an unusual case of primary extranodal immunocytoma involving the small intestine and discuss its clinicopathologic features.

Original languageEnglish
Pages (from-to)677-679
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume125
Issue number5
StatePublished - May 22 2001
Externally publishedYes

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Paraproteins
Waldenstrom Macroglobulinemia
Periodic Acid
Intestinal Obstruction
Plasma Cells
Ileum
Laparotomy
Small Intestine
Immunoglobulin M
Electrophoresis
Blood Proteins
Dilatation
Lymphocytes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Extranodal lymphoplasmacytoid lymphoma (immunocytoma) presenting as small intestinal obstruction : A case report and review of the literature. / Recine, Monica A.; Perez, Maria T.; Cabello-Inchausti, Beria; Lilenbaum, Rogerio C.; Robinson, Morton J.

In: Archives of Pathology and Laboratory Medicine, Vol. 125, No. 5, 22.05.2001, p. 677-679.

Research output: Contribution to journalArticle

Recine, Monica A. ; Perez, Maria T. ; Cabello-Inchausti, Beria ; Lilenbaum, Rogerio C. ; Robinson, Morton J. / Extranodal lymphoplasmacytoid lymphoma (immunocytoma) presenting as small intestinal obstruction : A case report and review of the literature. In: Archives of Pathology and Laboratory Medicine. 2001 ; Vol. 125, No. 5. pp. 677-679.
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