Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication

Bianca R. Mothé, Jason Weinfurter, Chenxi Wang, William Rehrauer, Nancy Wilson, Todd M. Allen, David B. Allison, David Watkins

Research output: Contribution to journalArticle

168 Citations (Scopus)

Abstract

Several HLA alleles are associated with attenuated human immunodeficiency virus disease progression. We explored the relationship between the expression of particular major histocompatibility complex (MHC) class I alleles and viremia in simian immunodeficiency virus SIVmac239-infected macaques. Of the common MHC class I alleles, animals that expressed Mamu-A*01 exhibited the best control of viral replication.

Original languageEnglish
Pages (from-to)2736-2740
Number of pages5
JournalJournal of Virology
Volume77
Issue number4
DOIs
StatePublished - Feb 1 2003
Externally publishedYes

Fingerprint

Simian immunodeficiency virus
Simian Immunodeficiency Virus
major histocompatibility complex
Virus Replication
virus replication
Major Histocompatibility Complex
Alleles
alleles
Viremia
viremia
Human immunodeficiency virus
Macaca
Virus Diseases
disease course
Disease Progression
HIV
animals

ASJC Scopus subject areas

  • Immunology

Cite this

Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication. / Mothé, Bianca R.; Weinfurter, Jason; Wang, Chenxi; Rehrauer, William; Wilson, Nancy; Allen, Todd M.; Allison, David B.; Watkins, David.

In: Journal of Virology, Vol. 77, No. 4, 01.02.2003, p. 2736-2740.

Research output: Contribution to journalArticle

Mothé, Bianca R. ; Weinfurter, Jason ; Wang, Chenxi ; Rehrauer, William ; Wilson, Nancy ; Allen, Todd M. ; Allison, David B. ; Watkins, David. / Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication. In: Journal of Virology. 2003 ; Vol. 77, No. 4. pp. 2736-2740.
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