Abstract
YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.
Original language | English (US) |
---|---|
Pages (from-to) | 5160-5166 |
Number of pages | 7 |
Journal | Journal of bacteriology |
Volume | 186 |
Issue number | 15 |
DOIs | |
State | Published - Aug 2004 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology