Abstract
YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.
| Original language | English |
|---|---|
| Pages (from-to) | 5160-5166 |
| Number of pages | 7 |
| Journal | Journal of Bacteriology |
| Volume | 186 |
| Issue number | 15 |
| DOIs | |
| State | Published - Aug 1 2004 |
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ASJC Scopus subject areas
- Applied Microbiology and Biotechnology
- Immunology
Cite this
Expression of a functional secreted YopN-TyeA hybrid protein in Yersinia pestis is the result of a +1 translational frameshift event. / Ferracci, Franco; Day, James B.; Ezelle, Heather J.; Plano, Gregory V.
In: Journal of Bacteriology, Vol. 186, No. 15, 01.08.2004, p. 5160-5166.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Expression of a functional secreted YopN-TyeA hybrid protein in Yersinia pestis is the result of a +1 translational frameshift event
AU - Ferracci, Franco
AU - Day, James B.
AU - Ezelle, Heather J.
AU - Plano, Gregory V
PY - 2004/8/1
Y1 - 2004/8/1
N2 - YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.
AB - YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.
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UR - http://www.scopus.com/inward/citedby.url?scp=3242750578&partnerID=8YFLogxK
U2 - 10.1128/JB.186.15.5160-5166.2004
DO - 10.1128/JB.186.15.5160-5166.2004
M3 - Article
C2 - 15262954
AN - SCOPUS:3242750578
VL - 186
SP - 5160
EP - 5166
JO - Journal of Bacteriology
JF - Journal of Bacteriology
SN - 0021-9193
IS - 15
ER -