Abstract
YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5160-5166 |
| Number of pages | 7 |
| Journal | Journal of bacteriology |
| Volume | 186 |
| Issue number | 15 |
| DOIs | |
| State | Published - Aug 2004 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
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Ferracci, F., Day, J. B., Ezelle, H. J., & Plano, G. V. (2004). Expression of a functional secreted YopN-TyeA hybrid protein in Yersinia pestis is the result of a +1 translational frameshift event. Journal of bacteriology, 186(15), 5160-5166. https://doi.org/10.1128/JB.186.15.5160-5166.2004