Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm

Nelson Salas, Fabrice Manns, Jean-Marie A Parel, Peter J. Milne, Manuel Figueroa, David B. Denham, David S. Robinson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The purpose of these experiments was to evaluate the temperature and predicted cell kill distribution during LITT of breast tissue phantoms at 940nm and compare with the results of previous experiments at 830 nm and 980 nm. Material and Methods: A Dornier Medilas D Skinpulse 940 nm diode laser system coupled to a Dornier D-6111-T2 fiber (Dornier Surgical Products, Phoenix, AZ) was used to irradiate the porcine tissue three times at approximately 5 W for 10 minutes. Results: The initial rate of temperature increase at 940 nm for locations 5, 10, and 15 mm from the fiber axis ranged from 0.076 to 0.142 °C/s, 0.027 to 0.041 °C/s, and 0.008 to 0.013 °C/s, respectively, while the maximum temperature increase ranged from 37.8 to 46.9 °C, 19.3 to 26.1 °C, 8.6 to 13.0 °C, respectively. Temperature curves had lower slopes at 940 nm than at 830 nm and 980 nm. The maximum temperature increase was higher at 940 nm than at 830 nm. Predicted area of 100% cell kill was approximately 2 cm by 2 cm. Conclusion: Results of experiments at 940 nm were more comparable to those at 980 nm than at 830 nm.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsW.T.W. Riese, K.E. Bartels, L.S. Bass, K.W. Gregory
Pages398-403
Number of pages6
Volume4609
DOIs
StatePublished - 2002
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII - San Jose, CA, United States
Duration: Jan 19 2002Jan 22 2002

Other

OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII
CountryUnited States
CitySan Jose, CA
Period1/19/021/22/02

Fingerprint

interstitials
Tissue
Lasers
lasers
Temperature
temperature
Phoenix (AZ)
fibers
Fibers
Experiments
cells
breast
Semiconductor lasers
semiconductor lasers
slopes
curves
products

Keywords

  • Breast
  • Diffusing tip
  • Fiber
  • Laser
  • Thermotherapy

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Salas, N., Manns, F., Parel, J-M. A., Milne, P. J., Figueroa, M., Denham, D. B., & Robinson, D. S. (2002). Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm. In W. T. W. Riese, K. E. Bartels, L. S. Bass, & K. W. Gregory (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4609, pp. 398-403) https://doi.org/10.1117/12.438871

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm. / Salas, Nelson; Manns, Fabrice; Parel, Jean-Marie A; Milne, Peter J.; Figueroa, Manuel; Denham, David B.; Robinson, David S.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / W.T.W. Riese; K.E. Bartels; L.S. Bass; K.W. Gregory. Vol. 4609 2002. p. 398-403.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Salas, N, Manns, F, Parel, J-MA, Milne, PJ, Figueroa, M, Denham, DB & Robinson, DS 2002, Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm. in WTW Riese, KE Bartels, LS Bass & KW Gregory (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4609, pp. 398-403, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, San Jose, CA, United States, 1/19/02. https://doi.org/10.1117/12.438871
Salas N, Manns F, Parel J-MA, Milne PJ, Figueroa M, Denham DB et al. Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm. In Riese WTW, Bartels KE, Bass LS, Gregory KW, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4609. 2002. p. 398-403 https://doi.org/10.1117/12.438871
Salas, Nelson ; Manns, Fabrice ; Parel, Jean-Marie A ; Milne, Peter J. ; Figueroa, Manuel ; Denham, David B. ; Robinson, David S. / Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 940 nm. Proceedings of SPIE - The International Society for Optical Engineering. editor / W.T.W. Riese ; K.E. Bartels ; L.S. Bass ; K.W. Gregory. Vol. 4609 2002. pp. 398-403
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abstract = "The purpose of these experiments was to evaluate the temperature and predicted cell kill distribution during LITT of breast tissue phantoms at 940nm and compare with the results of previous experiments at 830 nm and 980 nm. Material and Methods: A Dornier Medilas D Skinpulse 940 nm diode laser system coupled to a Dornier D-6111-T2 fiber (Dornier Surgical Products, Phoenix, AZ) was used to irradiate the porcine tissue three times at approximately 5 W for 10 minutes. Results: The initial rate of temperature increase at 940 nm for locations 5, 10, and 15 mm from the fiber axis ranged from 0.076 to 0.142 °C/s, 0.027 to 0.041 °C/s, and 0.008 to 0.013 °C/s, respectively, while the maximum temperature increase ranged from 37.8 to 46.9 °C, 19.3 to 26.1 °C, 8.6 to 13.0 °C, respectively. Temperature curves had lower slopes at 940 nm than at 830 nm and 980 nm. The maximum temperature increase was higher at 940 nm than at 830 nm. Predicted area of 100{\%} cell kill was approximately 2 cm by 2 cm. Conclusion: Results of experiments at 940 nm were more comparable to those at 980 nm than at 830 nm.",
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