Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm

Nelson Salas, Fabrice Manns, Jean-Marie A Parel, P. J. Milne, A. Minhaj, D. B. Denham, D. S. Robinson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsR.R. Anderson, K.E. Bartels, L.S. Bass, C.G. Garrett
Pages508-512
Number of pages5
Volume4244
DOIs
StatePublished - 2001
EventLaser in Surgery: Advanced Characterization, Therapeutics, and Systems XI - San Jose,CA, United States
Duration: Jun 20 2001Jun 23 2001

Other

OtherLaser in Surgery: Advanced Characterization, Therapeutics, and Systems XI
CountryUnited States
CitySan Jose,CA
Period6/20/016/23/01

Fingerprint

interstitials
Tissue
Lasers
fibers
Fibers
lasers
Radiation
Wavelength
Temperature
irradiation
temperature
Laser beam effects
radiation
thermocouples
Thermocouples
muscles
wavelengths
breast
Muscle
Semiconductor lasers

Keywords

  • Breast
  • Breast cancer
  • Hyperthermia
  • Infrared
  • Laser
  • Thermotherapy
  • Tissue

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Salas, N., Manns, F., Parel, J-M. A., Milne, P. J., Minhaj, A., Denham, D. B., & Robinson, D. S. (2001). Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. In R. R. Anderson, K. E. Bartels, L. S. Bass, & C. G. Garrett (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4244, pp. 508-512) https://doi.org/10.1117/12.427842

Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. / Salas, Nelson; Manns, Fabrice; Parel, Jean-Marie A; Milne, P. J.; Minhaj, A.; Denham, D. B.; Robinson, D. S.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.R. Anderson; K.E. Bartels; L.S. Bass; C.G. Garrett. Vol. 4244 2001. p. 508-512.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Salas, N, Manns, F, Parel, J-MA, Milne, PJ, Minhaj, A, Denham, DB & Robinson, DS 2001, Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. in RR Anderson, KE Bartels, LS Bass & CG Garrett (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4244, pp. 508-512, Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI, San Jose,CA, United States, 6/20/01. https://doi.org/10.1117/12.427842
Salas N, Manns F, Parel J-MA, Milne PJ, Minhaj A, Denham DB et al. Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. In Anderson RR, Bartels KE, Bass LS, Garrett CG, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4244. 2001. p. 508-512 https://doi.org/10.1117/12.427842
Salas, Nelson ; Manns, Fabrice ; Parel, Jean-Marie A ; Milne, P. J. ; Minhaj, A. ; Denham, D. B. ; Robinson, D. S. / Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. Proceedings of SPIE - The International Society for Optical Engineering. editor / R.R. Anderson ; K.E. Bartels ; L.S. Bass ; C.G. Garrett. Vol. 4244 2001. pp. 508-512
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abstract = "The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).",
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