Abstract
The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).
Original language | English (US) |
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Pages (from-to) | 508-512 |
Number of pages | 5 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 4244 |
DOIs | |
State | Published - Jan 1 2001 |
Event | Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI - San Jose,CA, United States Duration: Jun 20 2001 → Jun 23 2001 |
Keywords
- Breast
- Breast cancer
- Hyperthermia
- Infrared
- Laser
- Thermotherapy
- Tissue
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering