Abstract
The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
| Editors | R.R. Anderson, K.E. Bartels, L.S. Bass, C.G. Garrett |
| Pages | 508-512 |
| Number of pages | 5 |
| Volume | 4244 |
| DOIs | |
| State | Published - 2001 |
| Event | Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI - San Jose,CA, United States Duration: Jun 20 2001 → Jun 23 2001 |
Other
| Other | Laser in Surgery: Advanced Characterization, Therapeutics, and Systems XI |
|---|---|
| Country | United States |
| City | San Jose,CA |
| Period | 6/20/01 → 6/23/01 |
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Keywords
- Breast
- Breast cancer
- Hyperthermia
- Infrared
- Laser
- Thermotherapy
- Tissue
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Condensed Matter Physics
Cite this
Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm. / Salas, Nelson; Manns, Fabrice; Parel, Jean-Marie A; Milne, P. J.; Minhaj, A.; Denham, D. B.; Robinson, D. S.
Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.R. Anderson; K.E. Bartels; L.S. Bass; C.G. Garrett. Vol. 4244 2001. p. 508-512.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Experimental laser interstitial thermotherapy in ex-vivo porcine tissue at 980 nm and 830 nm
AU - Salas, Nelson
AU - Manns, Fabrice
AU - Parel, Jean-Marie A
AU - Milne, P. J.
AU - Minhaj, A.
AU - Denham, D. B.
AU - Robinson, D. S.
PY - 2001
Y1 - 2001
N2 - The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).
AB - The purpose of these experiments was to compare the temperature increase in ex-vivo porcine mammary chain tissue as a breast tissue model during interstitial laser irradiation with diode lasers emitting at 980 nm and 830 nm. Both wavelengths were delivered at 4.0 W for 10 minutes through a diffusing fiber inserted into ex-vivo porcine tissue. The temperature was measured with a set of 15 thermocouples placed 5, 10, and 15 mm from the fiber axis. The initial rate of temperature increase 5 mm away from the fiber tip was higher at 980 nm (0.12 to 0.20 °C/s) than at 830 nm (0.10 to 0.16 °C/s). At 10 mm and 15 mm (areas with less radiation), the rate was smaller than at 5 mm (<0.06 °C/s at 10 mm and <0.02 °C/s at 15 mm) for both wavelengths with no significant difference between the 980 nm and 830 nm radiation. The temperature increase at 5, 10 and 15 mm away from the fiber tip after 10 minutes of irradiation was higher at 980 nm (36 to 45 °C at 5mm, 14 to 30 °C at 10 mm and 9 to 17 °C at 15 mm) than at 830 nm (27 to 33 °C at 5 mm, 11 to 17 °C at 10 mm and 8 to 9 °C at 15 mm) after 10 minutes. These results were found to be highly dependent on tissue composition (muscle vs. fatty tissue).
KW - Breast
KW - Breast cancer
KW - Hyperthermia
KW - Infrared
KW - Laser
KW - Thermotherapy
KW - Tissue
UR - http://www.scopus.com/inward/record.url?scp=0034945311&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034945311&partnerID=8YFLogxK
U2 - 10.1117/12.427842
DO - 10.1117/12.427842
M3 - Conference contribution
VL - 4244
SP - 508
EP - 512
BT - Proceedings of SPIE - The International Society for Optical Engineering
A2 - Anderson, R.R.
A2 - Bartels, K.E.
A2 - Bass, L.S.
A2 - Garrett, C.G.
ER -