TY - JOUR
T1 - Experimental and clinical experience with tissue engineering techniques for urethral reconstruction
AU - Atala, Anthony
PY - 2002/5
Y1 - 2002/5
N2 - Tissue engineering has been proposed as a strategy for urethral reconstruction. This may involve matrices alone, wherein the body's natural ability to regenerate is used to orient or direct new tissue growth, or the use of matrices with cells. Acellular collagen matrices derived from donor bladder submucosa have been used both experimentally and clinically for onlay urethral replacement with good success at our center. If a tubularized urethral repair is needed, the use of cells on the collagen matrix is essential for adequate tissue formation. Tissue engineering techniques are useful for urethral reconstruction.
AB - Tissue engineering has been proposed as a strategy for urethral reconstruction. This may involve matrices alone, wherein the body's natural ability to regenerate is used to orient or direct new tissue growth, or the use of matrices with cells. Acellular collagen matrices derived from donor bladder submucosa have been used both experimentally and clinically for onlay urethral replacement with good success at our center. If a tubularized urethral repair is needed, the use of cells on the collagen matrix is essential for adequate tissue formation. Tissue engineering techniques are useful for urethral reconstruction.
UR - http://www.scopus.com/inward/record.url?scp=0036587089&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036587089&partnerID=8YFLogxK
U2 - 10.1016/S0094-0143(02)00033-2
DO - 10.1016/S0094-0143(02)00033-2
M3 - Review article
C2 - 12371238
AN - SCOPUS:0036587089
VL - 29
SP - 485
EP - 492
JO - Urologic Clinics of North America
JF - Urologic Clinics of North America
SN - 0094-0143
IS - 2
ER -