TY - JOUR
T1 - Experimental alpha chymotrypsin glaucoma studied by scanning electron microscopy
AU - Anderson, Douglas R.
N1 - Funding Information:
Glaucoma was produced in one eye of each of four owl monkeys. To accomplish this, a 27-gauge needle attached to a tuberculin syringe was introduced into the anterior chamber of the anesthetized monkeys. As much aqueous humor as possible was aspirated. The tip of the needle was then introduced through the pupil into the posterior chamber, and alpha chymotrypsin in a dilution of 1:1000 ( 750 units per ml) was From the Howe Laboratory of Ophthalmology, Boston. This study was supported in part by USPHS Research ('.rant NB-03951 and NIH Center Grant NB-05691 from the National Institute of Neurological Diseases and Blindness, Bethesda, Maryland. Dr. Anderson is currently at the Bascom Palmer Eye Institute, Miami, Florida, where he holds an RPB Eye Research Professorship awarded by Research to Prevent Blindness, Incorporated.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1971/2
Y1 - 1971/2
N2 - Glaucoma was produced experimentally in owl monkeys by injection of alpha chymotrypsin to the posterior chamber. Scanning electron microscopy shows that in the glaucomatous eyes the trabecular meshwork was obstructed by particulate matter. A few of the obstructing particles were erythrocytes, and leukocytes were also present; but most of the particles were identified as zonular fragments.
AB - Glaucoma was produced experimentally in owl monkeys by injection of alpha chymotrypsin to the posterior chamber. Scanning electron microscopy shows that in the glaucomatous eyes the trabecular meshwork was obstructed by particulate matter. A few of the obstructing particles were erythrocytes, and leukocytes were also present; but most of the particles were identified as zonular fragments.
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U2 - 10.1016/0002-9394(71)90120-6
DO - 10.1016/0002-9394(71)90120-6
M3 - Article
C2 - 4993915
AN - SCOPUS:0015015974
VL - 71
SP - 470
EP - 476
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 2
ER -