Expanded use of transplantation techniques: Abdominal wall transplantation and intestinal autotransplantation

G. Selvaggi, D. M. Levi, T. Kato, J. Madariaga, J. Moon, S. Nishida, A. G. Tzakis

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Surgical principles and techniques derived from organ transplantation surgery can provide novel applications in general surgery. We present an update on our 5-year experience with intestinal autotransplantation and abdominal wall transplantation. Nine patients underwent intestinal or multivisceral transplantation with the addition of 10 abdominal wall grafts to cover the large open areas from previous surgeries. Seven patients underwent near-total abdominal evisceration, ex vivo resection of masses at the base of the mesentery, followed by intestinal autotransplantation; 44% of the abdominal wall graft recipients are alive, but none of the fatalities were related to the graft itself. In two cases the graft had to be removed due to venous thrombosis. Of patients with intestinal autotransplants, 71% are alive with two mortalities due to recurrent metastatic malignancy. In only one case, the intestinal autograft had to be removed because of venous thrombosis. All surviving patients but one are on a regular diet; two are on supplemental enteral feeds. These results show that anastomotic and resection techniques derived from the experience in solid organ transplant can be utilized in complex wound closure, as is the case of abdominal wall transplantation, or resection of large retroperitoneal tumors with intestinal autotransplantation.

Original languageEnglish (US)
Pages (from-to)1561-1563
Number of pages3
JournalTransplantation proceedings
Volume36
Issue number5
DOIs
StatePublished - Jun 1 2004

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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