Exercise intervention attenuates emotional distress and natural killer cell decrements following notification of positive serologic status for HIV-1

Arthur R. LaPerriere, Michael H Antoni, Neil Schneiderman, Gail Ironson, Nancy Klimas, Panagiota V. Caralis, Mary Ann Fletcher

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

The impact of aerobic exercise training as a buffer of the affective distress and immune decrements which accompany the notification of HIV-1 antibody status in an AIDS risk group was studied. Fifty asymptomatic gay males with a pretraining fitness level of average or below (determined by predicted VO2 max) were randomly assigned to either an aerobic exercise training program or a no-contact control condition. After five weeks of training, at a point 72 hours before serostatus notification, psychometric, fitness and immunologic data were collected on all subjects. Psychometric and immunologic measures were again collected one-week postnotification. Seropositive controls showed significant increases in anxiety and depression, as well as decrements in natural killer cell number following notification whereas, seropositive exercisers showed no similar changes and in fact, resembled both seronegative groups. These findings suggest that concurrent changes in some affective and immunologic measures in response to an acute stressor might be attenuated by an experimentally manipulated aerobic exercise training intervention.

Original languageEnglish
Pages (from-to)229-242
Number of pages14
JournalBiofeedback and Self-Regulation
Volume15
Issue number3
DOIs
StatePublished - Sep 1 1990

Fingerprint

natural killer cells
distress
Human immunodeficiency virus 1
Natural Killer Cells
HIV-1
exercise
Exercise
risk groups
anxiety
education programs
Psychometrics
buffers
HIV Antibodies
antibodies
Buffers
Acquired Immunodeficiency Syndrome
Anxiety
Cell Count
Depression
Education

Keywords

  • aerobic exercise
  • AIDS risk group
  • emotional distress
  • HIV-1, HIV-1 diagnosis
  • psychoneuroimmunology

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

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