Abstract
While aging is associated with predictable phenotypic changes, with associated effects on cardiovascular physiology and related clinical manifestations, the timing and pace of aging is modifiable. Exercise has been demonstrated to moderate fundamental aspects of aging and related vulnerability to disease. Habitual physical activity and exercise is associated with relatively more youthful physiology and capacities extending from subcellular function to integrated organ systems. Even when seniors are already encumbered by age-related limitations or disease, aerobic, strength and other training regimens can help restore physical function, balance and flexibility, as well as inter-related dynamics of health. In this perspective, we describe age-related changes and vulnerabilities, particularly pertaining to the cardiovascular system and inter-related skeletal muscle health, and the utility of exercise training to allay aging and/or restore capacities even after aging encumbrances have started.
| Original language | English |
|---|---|
| Pages (from-to) | 473-482 |
| Number of pages | 10 |
| Journal | Aging Health |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 1 2013 |
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Keywords
- aging
- cardiorespiratory fitness
- cardiovascular
- diastole
- exercise
- myocardial compliance
- physical activity
- sarcopenia
- vascular stiffness
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Medicine(all)
Cite this
Exercise : A vital means to moderate cardiovascular aging. / Daniels, Karla; Arena, Ross; Lavie, Carl J.; Cahalin, Lawrence P; Forman, Daniel E.
In: Aging Health, Vol. 9, No. 5, 01.10.2013, p. 473-482.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Exercise
T2 - A vital means to moderate cardiovascular aging
AU - Daniels, Karla
AU - Arena, Ross
AU - Lavie, Carl J.
AU - Cahalin, Lawrence P
AU - Forman, Daniel E.
PY - 2013/10/1
Y1 - 2013/10/1
N2 - While aging is associated with predictable phenotypic changes, with associated effects on cardiovascular physiology and related clinical manifestations, the timing and pace of aging is modifiable. Exercise has been demonstrated to moderate fundamental aspects of aging and related vulnerability to disease. Habitual physical activity and exercise is associated with relatively more youthful physiology and capacities extending from subcellular function to integrated organ systems. Even when seniors are already encumbered by age-related limitations or disease, aerobic, strength and other training regimens can help restore physical function, balance and flexibility, as well as inter-related dynamics of health. In this perspective, we describe age-related changes and vulnerabilities, particularly pertaining to the cardiovascular system and inter-related skeletal muscle health, and the utility of exercise training to allay aging and/or restore capacities even after aging encumbrances have started.
AB - While aging is associated with predictable phenotypic changes, with associated effects on cardiovascular physiology and related clinical manifestations, the timing and pace of aging is modifiable. Exercise has been demonstrated to moderate fundamental aspects of aging and related vulnerability to disease. Habitual physical activity and exercise is associated with relatively more youthful physiology and capacities extending from subcellular function to integrated organ systems. Even when seniors are already encumbered by age-related limitations or disease, aerobic, strength and other training regimens can help restore physical function, balance and flexibility, as well as inter-related dynamics of health. In this perspective, we describe age-related changes and vulnerabilities, particularly pertaining to the cardiovascular system and inter-related skeletal muscle health, and the utility of exercise training to allay aging and/or restore capacities even after aging encumbrances have started.
KW - aging
KW - cardiorespiratory fitness
KW - cardiovascular
KW - diastole
KW - exercise
KW - myocardial compliance
KW - physical activity
KW - sarcopenia
KW - vascular stiffness
UR - http://www.scopus.com/inward/record.url?scp=84885100002&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885100002&partnerID=8YFLogxK
U2 - 10.2217/ahe.13.46
DO - 10.2217/ahe.13.46
M3 - Article
AN - SCOPUS:84885100002
VL - 9
SP - 473
EP - 482
JO - Aging Health
JF - Aging Health
SN - 1745-509X
IS - 5
ER -