Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

James F. Markmann, Stephen T. Bartlett, Paul Johnson, Olle Korsgren, Bernhard J. Hering, David Scharp, Thomas W H Kay, Jonathan Bromberg, Jon S. Odorico, Gordon C. Weir, Nancy Bridges, Raja Kandaswamy, Peter Stock, Peter Friend, Mitsukazu Gotoh, David K C Cooper, Chung Gyu Park, Philip J. O'Connell, Cherie Stabler, Shinichi MatsumotoBarbara Ludwig, Pratik Choudhary, Boris Khovatchev, Michael R. Rickels, Megan Sykes, Kathryn Wood, Kristy Kraemer, Albert Hwa, Edward Stanley, Camillo Ricordi, Mark Zimmerman, Julia Greenstein, Eduard Montanya, Timo Otonkoski

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16 Scopus citations

Abstract

The International Pancreas and Islet Transplant Association (IPITA), in conjunctionwith the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.

Original languageEnglish (US)
Pages (from-to)e25-e31
JournalTransplantation
Volume100
Issue number7
DOIs
StatePublished - Jun 21 2016

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ASJC Scopus subject areas

  • Transplantation

Cite this

Markmann, J. F., Bartlett, S. T., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P. J., Stabler, C., ... Otonkoski, T. (2016). Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement. Transplantation, 100(7), e25-e31. https://doi.org/10.1097/TP.0000000000001054