Exceptional response to FOLFIRINOX in a patient with pancreatic cancer and a germline RAD51C mutation

Sofia Palacio, Terri Pollack, Rachel Silva-Smith, Daniel A Sussman, Peter Hosein

Research output: Contribution to journalArticle

1 Scopus citations


Pancreatic cancer is projected to become the second leading cause of cancer death in the United States by 2030. Deleterious germline mutations can contribute to pancreatic cancer susceptibility. Herein we report a case of a patient with metastatic pancreatic adenocarcinoma to the lung and liver who was found to have a deleterious germline mutation in RAD51C who had a remarkable response to chemotherapy with FOLFIRINOX, a platinum-containing regimen.

Original languageEnglish (US)
Pages (from-to)E19-E22
JournalJournal of Gastrointestinal Oncology
Issue number4
StatePublished - Aug 1 2018



  • Oxaliplatin
  • Pancreatic adenocarcinoma
  • RAD51C

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

Cite this