Ex-vivo testing of crystalline lens substitutes: a pilot study

Marie Hamaoui, Jean Marie Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, Brien Holden

Research output: Contribution to journalConference article

Abstract

The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.

Original languageEnglish (US)
Pages (from-to)123-130
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3908
StatePublished - Jan 1 2000
EventOphthalmic Technologies X - San Jose, CA, USA
Duration: Jan 22 2000Jan 23 2000

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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