Ex-vivo testing of crystalline lens substitutes

a pilot study

Marie Hamaoui, Jean-Marie A Parel, Fabrice Manns, Hassan Tahi, Arthur Ho, Brien Holden

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages123-130
Number of pages8
Volume3908
StatePublished - 2000
EventOphthalmic Technologies X - San Jose, CA, USA
Duration: Jan 22 2000Jan 23 2000

Other

OtherOphthalmic Technologies X
CitySan Jose, CA, USA
Period1/22/001/23/00

Fingerprint

Lenses
lenses
substitutes
Crystalline materials
Testing
capsules
accommodation
cell culturing
Topography
topography
polymers
Polymers
rabbits

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Hamaoui, M., Parel, J-M. A., Manns, F., Tahi, H., Ho, A., & Holden, B. (2000). Ex-vivo testing of crystalline lens substitutes: a pilot study. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3908, pp. 123-130). Society of Photo-Optical Instrumentation Engineers.

Ex-vivo testing of crystalline lens substitutes : a pilot study. / Hamaoui, Marie; Parel, Jean-Marie A; Manns, Fabrice; Tahi, Hassan; Ho, Arthur; Holden, Brien.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3908 Society of Photo-Optical Instrumentation Engineers, 2000. p. 123-130.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hamaoui, M, Parel, J-MA, Manns, F, Tahi, H, Ho, A & Holden, B 2000, Ex-vivo testing of crystalline lens substitutes: a pilot study. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3908, Society of Photo-Optical Instrumentation Engineers, pp. 123-130, Ophthalmic Technologies X, San Jose, CA, USA, 1/22/00.
Hamaoui M, Parel J-MA, Manns F, Tahi H, Ho A, Holden B. Ex-vivo testing of crystalline lens substitutes: a pilot study. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3908. Society of Photo-Optical Instrumentation Engineers. 2000. p. 123-130
Hamaoui, Marie ; Parel, Jean-Marie A ; Manns, Fabrice ; Tahi, Hassan ; Ho, Arthur ; Holden, Brien. / Ex-vivo testing of crystalline lens substitutes : a pilot study. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3908 Society of Photo-Optical Instrumentation Engineers, 2000. pp. 123-130
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