Abstract
The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
| Publisher | Society of Photo-Optical Instrumentation Engineers |
| Pages | 123-130 |
| Number of pages | 8 |
| Volume | 3908 |
| State | Published - 2000 |
| Event | Ophthalmic Technologies X - San Jose, CA, USA Duration: Jan 22 2000 → Jan 23 2000 |
Other
| Other | Ophthalmic Technologies X |
|---|---|
| City | San Jose, CA, USA |
| Period | 1/22/00 → 1/23/00 |
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ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Condensed Matter Physics
Cite this
Ex-vivo testing of crystalline lens substitutes : a pilot study. / Hamaoui, Marie; Parel, Jean-Marie A; Manns, Fabrice; Tahi, Hassan; Ho, Arthur; Holden, Brien.
Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3908 Society of Photo-Optical Instrumentation Engineers, 2000. p. 123-130.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Ex-vivo testing of crystalline lens substitutes
T2 - a pilot study
AU - Hamaoui, Marie
AU - Parel, Jean-Marie A
AU - Manns, Fabrice
AU - Tahi, Hassan
AU - Ho, Arthur
AU - Holden, Brien
PY - 2000
Y1 - 2000
N2 - The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.
AB - The paper reviews two techniques being developed for ex-vivo testing of crystalline lens substitutes. The techniques may be used to test polymers developed for the Restore Accommodation (RA) project. Harvested rabbit and human lenses were used in preliminary tests to determine the feasibility of topographical analysis of the crystalline lens and ex-vivo cell culturing of the lens capsule. Lens capsules were cultured to test formation of posterior capsule opacification (PCO) in the presence of RA polymers. Feasibility of analyzing lens shape with the PAR Sys Corneal Topography System was determined using whole lenses. Preliminary results indicate that topography and cell culturing of lens capsules may be used to evaluate RA polymers.
UR - http://www.scopus.com/inward/record.url?scp=0033704896&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033704896&partnerID=8YFLogxK
M3 - Chapter
VL - 3908
SP - 123
EP - 130
BT - Proceedings of SPIE - The International Society for Optical Engineering
PB - Society of Photo-Optical Instrumentation Engineers
ER -