Evolving role of surgical treatment in limited‐disease small cell lung carcinoma

Kasi S. Sridhar, Atif M. Hussein, Richard J. Thurer

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The diagnostic role of surgical procedures in small cell lung carcinoma (SCLC) is well established. The therapeutic role of surgery has changed over the years. At present, curative resection is the treatment of choice in peripheral T1-2 N(o)M(o) SCLC, and adjuvant chemotherapy may be beneficial. Surgery is also indicated in SCLC patients diagnosed by a limited pathologic sample in whom the clinical course suggests nonsmall cell lung carcinoma (NSCLC). The resection may reveal either a mixed tumor or an alternate diagnosis and may be potentially curative. Surgery, at the time of maximal response to chemotherapy in T3N(o)M(o) SCLC, may be curative and reveal the presence of NSCLC elements. The best survival is in patients found to be tumor-free at surgery, and the worst survival is in N2 patients.

Original languageEnglish (US)
Pages (from-to)155-161
Number of pages7
JournalJournal of surgical oncology
Volume40
Issue number3
DOIs
StatePublished - Mar 1989

Keywords

  • adjuvant surgery
  • histologie conversion
  • mixed lung tumors
  • multimodality therapy
  • preoperative chemotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

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