Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions

Rachel A. Fayne, Francisco I. MacEdo, Steven E. Rodgers, Mecker G. Möller

Research output: Contribution to journalReview article

Abstract

Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph nodes recovered during CLND are only positive in a minority of these cases. Recent evidence suggests that conservative management (i.e. observation) has similar outcomes compared to CLND. We sought to review the most current literature regarding the management of SLN in metastatic melanoma and to discuss potential future directions.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalOncology Reviews
Volume13
Issue number2
DOIs
StatePublished - 2019

Keywords

  • Completion lymph node dissection
  • Melanoma
  • Sentinel lymph node biopsy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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