Evidence to Maintain the Systolic Blood Pressure Treatment Threshold at 140 mm Hg for Stroke Prevention: The Northern Manhattan Study

Chuanhui Dong, David Della Morte, Tatjana Rundek, Clinton B Wright, Mitchell S V Elkind, Ralph L Sacco

Research output: Contribution to journalArticle

12 Scopus citations


In 2014, the Eighth Joint National Committee revised the target maximum systolic blood pressure (SBP) from 140 to 150 mm Hg in patients aged ≥60 years without diabetes mellitus or chronic kidney disease. The evidence from cohort studies supporting this change was sparse, particularly among US minority populations. In the Northern Manhattan Study, 1750 participants aged ≥60 years and free of stroke, diabetes mellitus, and chronic kidney disease had SBP measured at baseline and were annually followed up for incident stroke. Mean age at baseline was 72±8 years, 63% were women, 48% Hispanic, 25% non-Hispanic white, and 25% non-Hispanic black. Among all participants, 40% were on antihypertensive medications; 43% had SBP

Original languageEnglish (US)
Pages (from-to)520-526
Number of pages7
Issue number3
StatePublished - Mar 1 2016



  • blood pressure
  • cardiovascular diseases
  • continental population groups
  • epidemiology
  • stroke

ASJC Scopus subject areas

  • Internal Medicine

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