Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons

Ian D. Hentall, Timothy R. White

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Raphe magnus cells that are inhibited by skin pinching fire spontaneously with strongly preferred interspike intervals (mean cycle 85 ms, n = 33). In pentobarbital-anesthetized rats, mid-cycle cathodal activation (0.3 ms) or end-cycle anodal block (30-60 ms) at ~ 1 Hz through the extracellular recording microelectrode delayed expected spikes; respective post-stimulus latencies peaked on avarage at 1.17 (n = 14) and 0.40 (n = 6) cycles. Feedback inhibition following random excitation, but not free-running intrinsic or afferent oscillations, may therefore cause the rhythm.

Original languageEnglish (US)
Pages (from-to)348-351
Number of pages4
JournalBrain Research
Volume745
Issue number1-2
DOIs
StatePublished - Jan 16 1997

Keywords

  • Autocorrelogram
  • Medulla
  • Microstimulation
  • Oscillation
  • Pain
  • Spike train

ASJC Scopus subject areas

  • Neuroscience(all)

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