Abstract
Raphe magnus cells that are inhibited by skin pinching fire spontaneously with strongly preferred interspike intervals (mean cycle 85 ms, n = 33). In pentobarbital-anesthetized rats, mid-cycle cathodal activation (0.3 ms) or end-cycle anodal block (30-60 ms) at ~ 1 Hz through the extracellular recording microelectrode delayed expected spikes; respective post-stimulus latencies peaked on avarage at 1.17 (n = 14) and 0.40 (n = 6) cycles. Feedback inhibition following random excitation, but not free-running intrinsic or afferent oscillations, may therefore cause the rhythm.
| Original language | English |
|---|---|
| Pages (from-to) | 348-351 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 745 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 16 1997 |
| Externally published | Yes |
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Keywords
- Autocorrelogram
- Medulla
- Microstimulation
- Oscillation
- Pain
- Spike train
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons. / Hentall, Ian; White, Timothy R.
In: Brain Research, Vol. 745, No. 1-2, 16.01.1997, p. 348-351.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons
AU - Hentall, Ian
AU - White, Timothy R.
PY - 1997/1/16
Y1 - 1997/1/16
N2 - Raphe magnus cells that are inhibited by skin pinching fire spontaneously with strongly preferred interspike intervals (mean cycle 85 ms, n = 33). In pentobarbital-anesthetized rats, mid-cycle cathodal activation (0.3 ms) or end-cycle anodal block (30-60 ms) at ~ 1 Hz through the extracellular recording microelectrode delayed expected spikes; respective post-stimulus latencies peaked on avarage at 1.17 (n = 14) and 0.40 (n = 6) cycles. Feedback inhibition following random excitation, but not free-running intrinsic or afferent oscillations, may therefore cause the rhythm.
AB - Raphe magnus cells that are inhibited by skin pinching fire spontaneously with strongly preferred interspike intervals (mean cycle 85 ms, n = 33). In pentobarbital-anesthetized rats, mid-cycle cathodal activation (0.3 ms) or end-cycle anodal block (30-60 ms) at ~ 1 Hz through the extracellular recording microelectrode delayed expected spikes; respective post-stimulus latencies peaked on avarage at 1.17 (n = 14) and 0.40 (n = 6) cycles. Feedback inhibition following random excitation, but not free-running intrinsic or afferent oscillations, may therefore cause the rhythm.
KW - Autocorrelogram
KW - Medulla
KW - Microstimulation
KW - Oscillation
KW - Pain
KW - Spike train
UR - http://www.scopus.com/inward/record.url?scp=0031029025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031029025&partnerID=8YFLogxK
U2 - 10.1016/S0006-8993(96)01236-X
DO - 10.1016/S0006-8993(96)01236-X
M3 - Article
C2 - 9037432
AN - SCOPUS:0031029025
VL - 745
SP - 348
EP - 351
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1-2
ER -