Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons

Ian D. Hentall; Timothy R. White

doi:10.1016/S0006-8993(96)01236-X

Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons

Ian D. Hentall, Timothy R. White

Neurological Surgery

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

Raphe magnus cells that are inhibited by skin pinching fire spontaneously with strongly preferred interspike intervals (mean cycle 85 ms, n = 33). In pentobarbital-anesthetized rats, mid-cycle cathodal activation (0.3 ms) or end-cycle anodal block (30-60 ms) at ~ 1 Hz through the extracellular recording microelectrode delayed expected spikes; respective post-stimulus latencies peaked on avarage at 1.17 (n = 14) and 0.40 (n = 6) cycles. Feedback inhibition following random excitation, but not free-running intrinsic or afferent oscillations, may therefore cause the rhythm.

Original language	English (US)
Pages (from-to)	348-351
Number of pages	4
Journal	Brain Research
Volume	745
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(96)01236-X
State	Published - Jan 16 1997

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Keywords

Autocorrelogram
Medulla
Microstimulation
Oscillation
Pain
Spike train

ASJC Scopus subject areas

Neuroscience(all)

Cite this

Hentall, I. D., & White, T. R. (1997). Evidence for rhythmic firing being caused by feedback inhibition in pinch-inhibited raphe magnus neurons. Brain Research, 745(1-2), 348-351. https://doi.org/10.1016/S0006-8993(96)01236-X

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10.1016/S0006-8993(96)01236-X