Evidence for posterior zonular fiber attachment on the anterior hyaloid membrane

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

PURPOSE. To image the posterior zonular attachment site by using environmental scanning electron microscopy (ESEM). METHODS. A custom-made device was designed to mount human cadaveric lenses, with the zonule, ciliary body, and sclera attached, inside an environmental scanning electron microscope (ESEM). The mount was designed to allow radial stretching to enhance exposure of the accommodation apparatus. Seven fresh human eye bank eyes (age: 62-82 years; 24-48 hours after death) were dissected, mounted, and imaged in wet mode. The insertion site of the posterior zonule was examined. RESULTS. Detailed pictures of the accommodation apparatus were obtained in all eyes. A strong relation between the posterior zonule and the anterior hyaloid membrane was observed. Anterior view micrographs showed that posterior zonular fibers originate from the ciliary body and anchor in the hyaloid membrane. From the point of insertion, the fibers continue on their course toward the posterior lens capsule in the plane of the hyaloid membrane. CONCLUSIONS. Contrary to the classic description, the majority of posterior zonular fibers are not attached directly to the posterior lens capsule, but are anchored to the anterior hyaloid membrane on their path from the ciliary body to the posterior capsule. This finding is in good agreement with several previous observations and models that suggest support of the posterior lens surface during accommodation.

Original languageEnglish
Pages (from-to)4708-4713
Number of pages6
JournalInvestigative Ophthalmology and Visual Science
Volume47
Issue number11
DOIs
StatePublished - Nov 1 2006

Fingerprint

Ciliary Body
Posterior Capsule of the Lens
Membranes
Lenses
Eye Banks
Sclera
Electron Scanning Microscopy
Capsules
Electrons
Equipment and Supplies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Evidence for posterior zonular fiber attachment on the anterior hyaloid membrane. / Bernal, Andres; Parel, Jean-Marie A; Manns, Fabrice.

In: Investigative Ophthalmology and Visual Science, Vol. 47, No. 11, 01.11.2006, p. 4708-4713.

Research output: Contribution to journalArticle

@article{c04f60b4313a43999f8d684a96f2b893,
title = "Evidence for posterior zonular fiber attachment on the anterior hyaloid membrane",
abstract = "PURPOSE. To image the posterior zonular attachment site by using environmental scanning electron microscopy (ESEM). METHODS. A custom-made device was designed to mount human cadaveric lenses, with the zonule, ciliary body, and sclera attached, inside an environmental scanning electron microscope (ESEM). The mount was designed to allow radial stretching to enhance exposure of the accommodation apparatus. Seven fresh human eye bank eyes (age: 62-82 years; 24-48 hours after death) were dissected, mounted, and imaged in wet mode. The insertion site of the posterior zonule was examined. RESULTS. Detailed pictures of the accommodation apparatus were obtained in all eyes. A strong relation between the posterior zonule and the anterior hyaloid membrane was observed. Anterior view micrographs showed that posterior zonular fibers originate from the ciliary body and anchor in the hyaloid membrane. From the point of insertion, the fibers continue on their course toward the posterior lens capsule in the plane of the hyaloid membrane. CONCLUSIONS. Contrary to the classic description, the majority of posterior zonular fibers are not attached directly to the posterior lens capsule, but are anchored to the anterior hyaloid membrane on their path from the ciliary body to the posterior capsule. This finding is in good agreement with several previous observations and models that suggest support of the posterior lens surface during accommodation.",
author = "Andres Bernal and Parel, {Jean-Marie A} and Fabrice Manns",
year = "2006",
month = "11",
day = "1",
doi = "10.1167/iovs.06-0441",
language = "English",
volume = "47",
pages = "4708--4713",
journal = "Investigative Ophthalmology and Visual Science",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "11",

}

TY - JOUR

T1 - Evidence for posterior zonular fiber attachment on the anterior hyaloid membrane

AU - Bernal, Andres

AU - Parel, Jean-Marie A

AU - Manns, Fabrice

PY - 2006/11/1

Y1 - 2006/11/1

N2 - PURPOSE. To image the posterior zonular attachment site by using environmental scanning electron microscopy (ESEM). METHODS. A custom-made device was designed to mount human cadaveric lenses, with the zonule, ciliary body, and sclera attached, inside an environmental scanning electron microscope (ESEM). The mount was designed to allow radial stretching to enhance exposure of the accommodation apparatus. Seven fresh human eye bank eyes (age: 62-82 years; 24-48 hours after death) were dissected, mounted, and imaged in wet mode. The insertion site of the posterior zonule was examined. RESULTS. Detailed pictures of the accommodation apparatus were obtained in all eyes. A strong relation between the posterior zonule and the anterior hyaloid membrane was observed. Anterior view micrographs showed that posterior zonular fibers originate from the ciliary body and anchor in the hyaloid membrane. From the point of insertion, the fibers continue on their course toward the posterior lens capsule in the plane of the hyaloid membrane. CONCLUSIONS. Contrary to the classic description, the majority of posterior zonular fibers are not attached directly to the posterior lens capsule, but are anchored to the anterior hyaloid membrane on their path from the ciliary body to the posterior capsule. This finding is in good agreement with several previous observations and models that suggest support of the posterior lens surface during accommodation.

AB - PURPOSE. To image the posterior zonular attachment site by using environmental scanning electron microscopy (ESEM). METHODS. A custom-made device was designed to mount human cadaveric lenses, with the zonule, ciliary body, and sclera attached, inside an environmental scanning electron microscope (ESEM). The mount was designed to allow radial stretching to enhance exposure of the accommodation apparatus. Seven fresh human eye bank eyes (age: 62-82 years; 24-48 hours after death) were dissected, mounted, and imaged in wet mode. The insertion site of the posterior zonule was examined. RESULTS. Detailed pictures of the accommodation apparatus were obtained in all eyes. A strong relation between the posterior zonule and the anterior hyaloid membrane was observed. Anterior view micrographs showed that posterior zonular fibers originate from the ciliary body and anchor in the hyaloid membrane. From the point of insertion, the fibers continue on their course toward the posterior lens capsule in the plane of the hyaloid membrane. CONCLUSIONS. Contrary to the classic description, the majority of posterior zonular fibers are not attached directly to the posterior lens capsule, but are anchored to the anterior hyaloid membrane on their path from the ciliary body to the posterior capsule. This finding is in good agreement with several previous observations and models that suggest support of the posterior lens surface during accommodation.

UR - http://www.scopus.com/inward/record.url?scp=34247148945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247148945&partnerID=8YFLogxK

U2 - 10.1167/iovs.06-0441

DO - 10.1167/iovs.06-0441

M3 - Article

C2 - 17065477

AN - SCOPUS:34247148945

VL - 47

SP - 4708

EP - 4713

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

IS - 11

ER -