Evidence for peptide nature of LH and FSH-releasing hormones

A. V. Schally, Y. Baba, A. Arimura, T. W. Redding, W. F. White

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

The effects of several chemical and enzymatic treatments on the biological activity of highly purified porcine luteinizing hormone-releasing hormone (LH-RH) and follicle-stimulating hormone-releasing hormone (FSH-RH) (1) were studied in an attempt to define the chemical nature of these hypothalamic hormones. The results obtained are consistent with the concept that LH-RH/FSH-RH activity is due to small basic polypeptide(s), but a conclusive differentiation between LH-RH and FSH-RH cannot yet be made.

Original languageEnglish (US)
Pages (from-to)50-56
Number of pages7
JournalBiochemical and biophysical research communications
Volume42
Issue number1
DOIs
StatePublished - Jan 8 1971
Externally publishedYes

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ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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