Evidence for peptide nature of LH and FSH-releasing hormones

Andrew V Schally, Y. Baba, A. Arimura, T. W. Redding, W. F. White

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The effects of several chemical and enzymatic treatments on the biological activity of highly purified porcine luteinizing hormone-releasing hormone (LH-RH) and follicle-stimulating hormone-releasing hormone (FSH-RH) (1) were studied in an attempt to define the chemical nature of these hypothalamic hormones. The results obtained are consistent with the concept that LH-RH/FSH-RH activity is due to small basic polypeptide(s), but a conclusive differentiation between LH-RH and FSH-RH cannot yet be made.

Original languageEnglish
Pages (from-to)50-56
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume42
Issue number1
DOIs
StatePublished - Jan 8 1971
Externally publishedYes

Fingerprint

Follicle Stimulating Hormone
Gonadotropin-Releasing Hormone
Hormones
Peptides
Hypothalamic Hormones
Bioactivity
Swine

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Evidence for peptide nature of LH and FSH-releasing hormones. / Schally, Andrew V; Baba, Y.; Arimura, A.; Redding, T. W.; White, W. F.

In: Biochemical and Biophysical Research Communications, Vol. 42, No. 1, 08.01.1971, p. 50-56.

Research output: Contribution to journalArticle

Schally, Andrew V ; Baba, Y. ; Arimura, A. ; Redding, T. W. ; White, W. F. / Evidence for peptide nature of LH and FSH-releasing hormones. In: Biochemical and Biophysical Research Communications. 1971 ; Vol. 42, No. 1. pp. 50-56.
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