Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin

Abigail S Hackam, J. Graeme Hodgson, Roshni Singaraja, Taiqi Zhang, Lu Gan, Claire Anne Gutekunst, Steven M. Hersch, Michael R. Hayden

Research output: Contribution to journalArticle

20 Scopus citations
Original languageEnglish
Pages (from-to)1047-1055
Number of pages9
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume354
Issue number1386
StatePublished - Jun 29 1999
Externally publishedYes

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Keywords

  • Aggregates
  • Animal model
  • Huntington's disease
  • In vitro
  • Pathogenesis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)

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