Evidence-based treatment paradigms for depressed patients with pain and physical symptoms.

David A. Fishbain

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Some antidepressants may be efficacious in alleviating pain. While few studies have directly compared antidepressants for the treatment of painful physical symptoms, meta-analyses of efficacy studies have found that antidepressants that act at serotonergic and noradrenergic neurotransmitters, such as some tricyclics and serotonin- norepinephrine reuptake inhibitors (SNRIs), may alleviate pain independently of their effects on mood. These dual-action agents have more consistently shown efficacy for pain than single-action agents.

Original languageEnglish (US)
Pages (from-to)e22
JournalThe Journal of clinical psychiatry
Volume70
Issue number7
DOIs
StatePublished - Jul 2009

ASJC Scopus subject areas

  • Psychiatry and Mental health

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