Abstract
Purpose of Review: Commercialization of an automated epidermal harvesting device (CelluTome™, Kinetic Concepts Inc., San Antonio, TX) in the last 6 years has led to numerous publications describing a growing number of clinical applications. The current article reviews this literature while summarizing outcomes. Recent Findings: A total of 20 published reports including 284 automated graft recipients have been published. Complete reepithelialization occurs in 50–92% of recipient sites, often within 4–18 weeks of graft placement. Donor sites heal without scarring within 1–2 weeks. Summary: Current evidence suggests efficacy in using an automated epidermal harvesting device for the wounds of patients with multiple comorbidities and failing previous treatments for their wounds, including vascular ulcers, diabetic ulcers, surgical wounds, complex wounds, acute traumatic wounds, pyoderma gangrenosum, and burns. Limited evidence also suggests efficacy of automated epidermal grafting for disorders of pigmentation. Better trials studying individual clinical applications of epidermal grafting are needed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 182-189 |
| Number of pages | 8 |
| Journal | Current Dermatology Reports |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1 2019 |
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Keywords
- Epidermal skin graft
- Pigmentation disorders
- Vitiligo
- Wound healing
ASJC Scopus subject areas
- Dermatology
Cite this
Evidence-Based Review of Clinical Applications and Outcomes of Automated Epidermal Grafting. / Qureshi, Azam A.; Kirsner, Robert S.
In: Current Dermatology Reports, Vol. 8, No. 4, 01.12.2019, p. 182-189.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Evidence-Based Review of Clinical Applications and Outcomes of Automated Epidermal Grafting
AU - Qureshi, Azam A.
AU - Kirsner, Robert S.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Purpose of Review: Commercialization of an automated epidermal harvesting device (CelluTome™, Kinetic Concepts Inc., San Antonio, TX) in the last 6 years has led to numerous publications describing a growing number of clinical applications. The current article reviews this literature while summarizing outcomes. Recent Findings: A total of 20 published reports including 284 automated graft recipients have been published. Complete reepithelialization occurs in 50–92% of recipient sites, often within 4–18 weeks of graft placement. Donor sites heal without scarring within 1–2 weeks. Summary: Current evidence suggests efficacy in using an automated epidermal harvesting device for the wounds of patients with multiple comorbidities and failing previous treatments for their wounds, including vascular ulcers, diabetic ulcers, surgical wounds, complex wounds, acute traumatic wounds, pyoderma gangrenosum, and burns. Limited evidence also suggests efficacy of automated epidermal grafting for disorders of pigmentation. Better trials studying individual clinical applications of epidermal grafting are needed.
AB - Purpose of Review: Commercialization of an automated epidermal harvesting device (CelluTome™, Kinetic Concepts Inc., San Antonio, TX) in the last 6 years has led to numerous publications describing a growing number of clinical applications. The current article reviews this literature while summarizing outcomes. Recent Findings: A total of 20 published reports including 284 automated graft recipients have been published. Complete reepithelialization occurs in 50–92% of recipient sites, often within 4–18 weeks of graft placement. Donor sites heal without scarring within 1–2 weeks. Summary: Current evidence suggests efficacy in using an automated epidermal harvesting device for the wounds of patients with multiple comorbidities and failing previous treatments for their wounds, including vascular ulcers, diabetic ulcers, surgical wounds, complex wounds, acute traumatic wounds, pyoderma gangrenosum, and burns. Limited evidence also suggests efficacy of automated epidermal grafting for disorders of pigmentation. Better trials studying individual clinical applications of epidermal grafting are needed.
KW - Epidermal skin graft
KW - Pigmentation disorders
KW - Vitiligo
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=85076526433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85076526433&partnerID=8YFLogxK
U2 - 10.1007/s13671-019-00270-5
DO - 10.1007/s13671-019-00270-5
M3 - Review article
AN - SCOPUS:85076526433
VL - 8
SP - 182
EP - 189
JO - Current Dermatology Reports
JF - Current Dermatology Reports
SN - 2162-4933
IS - 4
ER -