Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India

Raymond L. Ownby; Drenna Waldrop-Valverde; Deborah L. Jones; Sunil Sharma; Ritu Nehra; Adarsh M. Kumar; Sudesh Prabhakar; Amarilis Acevedo; Mahendra Kumar

doi:10.1007/s13365-016-0487-7

Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India

Raymond L. Ownby, Drenna Waldrop-Valverde, Deborah L. Jones, Sunil Sharma, Ritu Nehra, Adarsh M. Kumar, Sudesh Prabhakar, Amarilis Acevedo, Mahendra Kumar

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally by using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated 1 year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.

Original language	English (US)
Pages (from-to)	134-140
Number of pages	7
Journal	Journal of neurovirology
Volume	23
Issue number	1
DOIs	https://doi.org/10.1007/s13365-016-0487-7
State	Published - Feb 1 2017

Keywords

India
Longitudinal assessment
Neurocognitive
Practice effect

ASJC Scopus subject areas

Neurology
Clinical Neurology
Cellular and Molecular Neuroscience
Virology

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Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India. / Ownby, Raymond L.; Waldrop-Valverde, Drenna; Jones, Deborah L.; Sharma, Sunil; Nehra, Ritu; Kumar, Adarsh M.; Prabhakar, Sudesh; Acevedo, Amarilis; Kumar, Mahendra.

In: Journal of neurovirology, Vol. 23, No. 1, 01.02.2017, p. 134-140.

Research output: Contribution to journal › Article › peer-review

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AU - Kumar, Adarsh M.

AU - Prabhakar, Sudesh

AU - Acevedo, Amarilis

AU - Kumar, Mahendra

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