Abstract
An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally by using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated 1 year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-7 |
| Number of pages | 7 |
| Journal | Journal of NeuroVirology |
| DOIs | |
| State | Accepted/In press - Oct 13 2016 |
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Keywords
- India
- Longitudinal assessment
- Neurocognitive
- Practice effect
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Virology
Cite this
Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India. / Ownby, Raymond L.; Waldrop-Valverde, Drenna; Jones, Deborah; Sharma, Sunil; Nehra, Ritu; Kumar, Adarsh; Prabhakar, Sudesh; Acevedo, Amarilis; Kumar, Mahendra.
In: Journal of NeuroVirology, 13.10.2016, p. 1-7.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of practice effect on neuropsychological measures among persons with and without HIV infection in northern India
AU - Ownby, Raymond L.
AU - Waldrop-Valverde, Drenna
AU - Jones, Deborah
AU - Sharma, Sunil
AU - Nehra, Ritu
AU - Kumar, Adarsh
AU - Prabhakar, Sudesh
AU - Acevedo, Amarilis
AU - Kumar, Mahendra
PY - 2016/10/13
Y1 - 2016/10/13
N2 - An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally by using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated 1 year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.
AB - An evaluation of the effects of HIV infection on neurocognition over time is important for understanding disease progression. Changes in cognitive function can be evaluated longitudinally by using neuropsychological testing at repeated intervals. The assessment of change over time, however, is complicated by the potentially confounding influence of learning on repeated test administrations, often referred to as practice effect. In this study, we present data on testing of persons with or without HIV infection on a battery administered at study baseline and repeated 1 year later. Results suggest that practice effects may be diminished in persons with HIV infection compared to without it. This appears to be true even among those with relatively intact immune functioning as measured by CD4 count.
KW - India
KW - Longitudinal assessment
KW - Neurocognitive
KW - Practice effect
UR - http://www.scopus.com/inward/record.url?scp=84991044116&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84991044116&partnerID=8YFLogxK
U2 - 10.1007/s13365-016-0487-7
DO - 10.1007/s13365-016-0487-7
M3 - Article
C2 - 27739034
AN - SCOPUS:84991044116
SP - 1
EP - 7
JO - Journal of NeuroVirology
JF - Journal of NeuroVirology
SN - 1355-0284
ER -