Evaluation of myocardial ischemia in coronary artery disease with cardiac MR perfusion method: Comparison with the results of catheter or CT angiography

Mehmet Sait Doǧan, Erkan Yilmaz, Sümeyra Doǧan, Bahri Akdeniz, Nezihi Bariş, Uygar Teomete, Leyla Iyilikçi

Research output: Contribution to journalArticle

Abstract

Aim To evaluate the eficacy of the Cardiac Magnetic Resonance Perfusion (CMRP) method in detection of Coronary Artery Disease (CAD) by comparing CMRP indings with the results of Coronary Computed Tomography Angiography (CCTA) or Catheter Coronary Angiography (CCA). Methods Thirty one patients in whom CMRP was performed along with CCTA or CCA within a month after CMRP between December 2009 and November 2010 were selected for the study. In CMRP, after adenosine administration as a stress agent Balanced TFE sequences were used to gather dynamic images that include the myocardial irst pass of contrast media. Image analysis was performed visually. CMRP indings were compared to CCTA or CCA results for each coronary artery territories and for all territories. Results Sensitivity, speciicity, accuracy, positive predictive value, and negative predictive value of CMRP test in the identiication of patients with signiicant (≥70%) coronary artery stenosis were 94.7%, 83%, 90.3%, 90%, and 90.9% for all coronary arteries, respectively; 94.4%, 84.6%, 90.3%, 89.4%, and 91.6% for left anterior descending artery, respectively; and 100%, 100%, 100%, 100%, and 100% for circumlex and right coronary artery, respectively. There was no statistically signiicant difference between angiography methods (CCTA/CCA) and CMRP (p>0.05). Methods had good to perfect consistency (K{green} = 0.79-1.00). Conclusion CMRP test seems to be a reasonable alternative for catheter angiography, which is considered the gold standard for evaluation of CAD and exclusion of signiicant coronary artery obstruction.

Original languageEnglish
Pages (from-to)63-69
Number of pages7
JournalMedicinski Glasnik
Volume10
Issue number1
StatePublished - Feb 4 2013

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Myocardial Ischemia
Coronary Artery Disease
Magnetic Resonance Spectroscopy
Catheters
Perfusion
Coronary Angiography
Coronary Vessels
Computed Tomography Angiography
Coronary Stenosis
Polytetrafluoroethylene
Adenosine
Contrast Media
Angiography
Arteries

Keywords

  • Cardiac catheterization
  • Computed tomography
  • Coronary angiography
  • Perfusion magnetic resonance imaging

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Doǧan, M. S., Yilmaz, E., Doǧan, S., Akdeniz, B., Bariş, N., Teomete, U., & Iyilikçi, L. (2013). Evaluation of myocardial ischemia in coronary artery disease with cardiac MR perfusion method: Comparison with the results of catheter or CT angiography. Medicinski Glasnik, 10(1), 63-69.

Evaluation of myocardial ischemia in coronary artery disease with cardiac MR perfusion method : Comparison with the results of catheter or CT angiography. / Doǧan, Mehmet Sait; Yilmaz, Erkan; Doǧan, Sümeyra; Akdeniz, Bahri; Bariş, Nezihi; Teomete, Uygar; Iyilikçi, Leyla.

In: Medicinski Glasnik, Vol. 10, No. 1, 04.02.2013, p. 63-69.

Research output: Contribution to journalArticle

Doǧan, MS, Yilmaz, E, Doǧan, S, Akdeniz, B, Bariş, N, Teomete, U & Iyilikçi, L 2013, 'Evaluation of myocardial ischemia in coronary artery disease with cardiac MR perfusion method: Comparison with the results of catheter or CT angiography', Medicinski Glasnik, vol. 10, no. 1, pp. 63-69.
Doǧan, Mehmet Sait ; Yilmaz, Erkan ; Doǧan, Sümeyra ; Akdeniz, Bahri ; Bariş, Nezihi ; Teomete, Uygar ; Iyilikçi, Leyla. / Evaluation of myocardial ischemia in coronary artery disease with cardiac MR perfusion method : Comparison with the results of catheter or CT angiography. In: Medicinski Glasnik. 2013 ; Vol. 10, No. 1. pp. 63-69.
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abstract = "Aim To evaluate the eficacy of the Cardiac Magnetic Resonance Perfusion (CMRP) method in detection of Coronary Artery Disease (CAD) by comparing CMRP indings with the results of Coronary Computed Tomography Angiography (CCTA) or Catheter Coronary Angiography (CCA). Methods Thirty one patients in whom CMRP was performed along with CCTA or CCA within a month after CMRP between December 2009 and November 2010 were selected for the study. In CMRP, after adenosine administration as a stress agent Balanced TFE sequences were used to gather dynamic images that include the myocardial irst pass of contrast media. Image analysis was performed visually. CMRP indings were compared to CCTA or CCA results for each coronary artery territories and for all territories. Results Sensitivity, speciicity, accuracy, positive predictive value, and negative predictive value of CMRP test in the identiication of patients with signiicant (≥70{\%}) coronary artery stenosis were 94.7{\%}, 83{\%}, 90.3{\%}, 90{\%}, and 90.9{\%} for all coronary arteries, respectively; 94.4{\%}, 84.6{\%}, 90.3{\%}, 89.4{\%}, and 91.6{\%} for left anterior descending artery, respectively; and 100{\%}, 100{\%}, 100{\%}, 100{\%}, and 100{\%} for circumlex and right coronary artery, respectively. There was no statistically signiicant difference between angiography methods (CCTA/CCA) and CMRP (p>0.05). Methods had good to perfect consistency (K{green} = 0.79-1.00). Conclusion CMRP test seems to be a reasonable alternative for catheter angiography, which is considered the gold standard for evaluation of CAD and exclusion of signiicant coronary artery obstruction.",
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AU - Doǧan, Mehmet Sait

AU - Yilmaz, Erkan

AU - Doǧan, Sümeyra

AU - Akdeniz, Bahri

AU - Bariş, Nezihi

AU - Teomete, Uygar

AU - Iyilikçi, Leyla

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N2 - Aim To evaluate the eficacy of the Cardiac Magnetic Resonance Perfusion (CMRP) method in detection of Coronary Artery Disease (CAD) by comparing CMRP indings with the results of Coronary Computed Tomography Angiography (CCTA) or Catheter Coronary Angiography (CCA). Methods Thirty one patients in whom CMRP was performed along with CCTA or CCA within a month after CMRP between December 2009 and November 2010 were selected for the study. In CMRP, after adenosine administration as a stress agent Balanced TFE sequences were used to gather dynamic images that include the myocardial irst pass of contrast media. Image analysis was performed visually. CMRP indings were compared to CCTA or CCA results for each coronary artery territories and for all territories. Results Sensitivity, speciicity, accuracy, positive predictive value, and negative predictive value of CMRP test in the identiication of patients with signiicant (≥70%) coronary artery stenosis were 94.7%, 83%, 90.3%, 90%, and 90.9% for all coronary arteries, respectively; 94.4%, 84.6%, 90.3%, 89.4%, and 91.6% for left anterior descending artery, respectively; and 100%, 100%, 100%, 100%, and 100% for circumlex and right coronary artery, respectively. There was no statistically signiicant difference between angiography methods (CCTA/CCA) and CMRP (p>0.05). Methods had good to perfect consistency (K{green} = 0.79-1.00). Conclusion CMRP test seems to be a reasonable alternative for catheter angiography, which is considered the gold standard for evaluation of CAD and exclusion of signiicant coronary artery obstruction.

AB - Aim To evaluate the eficacy of the Cardiac Magnetic Resonance Perfusion (CMRP) method in detection of Coronary Artery Disease (CAD) by comparing CMRP indings with the results of Coronary Computed Tomography Angiography (CCTA) or Catheter Coronary Angiography (CCA). Methods Thirty one patients in whom CMRP was performed along with CCTA or CCA within a month after CMRP between December 2009 and November 2010 were selected for the study. In CMRP, after adenosine administration as a stress agent Balanced TFE sequences were used to gather dynamic images that include the myocardial irst pass of contrast media. Image analysis was performed visually. CMRP indings were compared to CCTA or CCA results for each coronary artery territories and for all territories. Results Sensitivity, speciicity, accuracy, positive predictive value, and negative predictive value of CMRP test in the identiication of patients with signiicant (≥70%) coronary artery stenosis were 94.7%, 83%, 90.3%, 90%, and 90.9% for all coronary arteries, respectively; 94.4%, 84.6%, 90.3%, 89.4%, and 91.6% for left anterior descending artery, respectively; and 100%, 100%, 100%, 100%, and 100% for circumlex and right coronary artery, respectively. There was no statistically signiicant difference between angiography methods (CCTA/CCA) and CMRP (p>0.05). Methods had good to perfect consistency (K{green} = 0.79-1.00). Conclusion CMRP test seems to be a reasonable alternative for catheter angiography, which is considered the gold standard for evaluation of CAD and exclusion of signiicant coronary artery obstruction.

KW - Cardiac catheterization

KW - Computed tomography

KW - Coronary angiography

KW - Perfusion magnetic resonance imaging

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