Evaluation of maternal cerebral circulation by transcranial Doppler in normal and abnormal pregnancies

V. Demarin, T. Rundek, B. Hodek

Research output: Contribution to journalArticlepeer-review


In order to evaluate the maternal cerebral blood flow changes in normal and abnormal pregnancies, we examined 40 gravidas by Transcranial Doppler (TCD), Color Doppler Flow Imaging (CDFI) of carotid arteries, and Transcranial Color Coded System (TCCS). Results of our study showed the degree of impairment in gestosis as measured by Goecke's index to significantly correlate with abnormal cerebral blood flow as assessed by TCD (p<0.01). The increase in blood flow velocities in almost all branches of the Willis' circle was the most prominent finding, recorded in 70% of abnormal pregnancies. No statistically significant difference in the M1 segment of the middle cerebral artery (MCA) diameters was found between normal (3.3 ± 0.7 mm) and abnormal pregnancies (3.1 ± 0.5 mm). The diameter of M1 did not significantly change during pregnancy, even in the gravidas with a high increase in the MCA blood flow velocities. Cerebral hemodynamic changes were reversible and normalized two months after delivery (p<0.01). Blood flow changes preceded neurologic symptoms in gestosis. The predictive value of the TCD assessment of cerebral hemodynamics in abnormal pregnancies was introduced.

Original languageEnglish (US)
Pages (from-to)3-7
Number of pages5
JournalActa Clinica Croatica
Issue number1-2
StatePublished - Jan 1 1996
Externally publishedYes


  • Complications
  • Doppler
  • Gestosis
  • Pregnancy
  • Transcranial
  • Ultrasonography
  • Vasospasm

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Evaluation of maternal cerebral circulation by transcranial Doppler in normal and abnormal pregnancies'. Together they form a unique fingerprint.

Cite this