Evaluation of lenticonus in Alport's syndrome: Quantitative scheimpflug analysis

Wei Zhou, Marc Hirsch, Anna Junk, Daniel S. Casper, Richard Braunstein, Janice David, Basil V. Worgul

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Anterior lenticonus is an ocular abnormality that can occur in Alport's syndrome. In this study, Scheimpflug slit imaging analyses were employed for quantitative and objective evaluation of lens changes associated with Alport's syndrome. It was determined that while the apices of the lenticular protrusions are central in the vertical plane, they are nasally displaced in the horizontal meridian. The eccentricity and dimensions of the diameters and thicknesses of the conical aberration are highly correlated in both eyes. Lens thickness and anterior chamber depth do not differ between eyes. Densitometrically similar differences are apparent in the cortex and nuclear regions although evidence of overt opacification may or may not be present. The data strongly suggest that the physical parameters of the lenticonus are consistent with the constraints imposed by the pupil. Changes observed in the cornea and the vitreous may be associated with the syndrome.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalOphthalmologica
Volume217
Issue number3
DOIs
StatePublished - Apr 2 2003
Externally publishedYes

Fingerprint

Hereditary Nephritis
Lenses
Eye Abnormalities
Meridians
Anterior Chamber
Pupil
Cornea

Keywords

  • Alport's syndrome
  • Biometry
  • Cataract
  • Cornea
  • Densitometry
  • Lens
  • Lenticonus
  • Quantitative assessment
  • Scheimpflug imaging
  • Vitreous

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Zhou, W., Hirsch, M., Junk, A., Casper, D. S., Braunstein, R., David, J., & Worgul, B. V. (2003). Evaluation of lenticonus in Alport's syndrome: Quantitative scheimpflug analysis. Ophthalmologica, 217(3), 189-193. https://doi.org/10.1159/000068978

Evaluation of lenticonus in Alport's syndrome : Quantitative scheimpflug analysis. / Zhou, Wei; Hirsch, Marc; Junk, Anna; Casper, Daniel S.; Braunstein, Richard; David, Janice; Worgul, Basil V.

In: Ophthalmologica, Vol. 217, No. 3, 02.04.2003, p. 189-193.

Research output: Contribution to journalArticle

Zhou, W, Hirsch, M, Junk, A, Casper, DS, Braunstein, R, David, J & Worgul, BV 2003, 'Evaluation of lenticonus in Alport's syndrome: Quantitative scheimpflug analysis', Ophthalmologica, vol. 217, no. 3, pp. 189-193. https://doi.org/10.1159/000068978
Zhou, Wei ; Hirsch, Marc ; Junk, Anna ; Casper, Daniel S. ; Braunstein, Richard ; David, Janice ; Worgul, Basil V. / Evaluation of lenticonus in Alport's syndrome : Quantitative scheimpflug analysis. In: Ophthalmologica. 2003 ; Vol. 217, No. 3. pp. 189-193.
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