Evaluation of cystography for detection of bladder carcinoma in mice Comparison with Urinary Cytology

Israel Nissenkorn; Lee McCallum; William N. Crabtree; William M. Murphy; Mark S. Soloway

doi:10.1016/0090-4295(81)90499-4

Evaluation of cystography for detection of bladder carcinoma in mice Comparison with Urinary Cytology

Israel Nissenkorn, Lee McCallum, William N. Crabtree, William M. Murphy, Mark S. Soloway

Urology

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Abstract

Cystography was compared to urinary cytology in an effort to determine whether or not this modality might be useful in the detection of FANFT-induced bladder tumors in mice. Compared to gross examination of the bladders in 24 mice, cystography had the same degree of accuracy as urinary cytology - 79.2 per cent. Comparison of the cystographic and cytologic diagnoses with histology revealed that cytology was more accurate, 79.2 vs 66.6 per cent. Cystography was especially helpful in detecting papillary tumors while cytology was more accurate in the detection of high-grade, high-stage tumors or carcinoma in situ (CIS). Cystography in mice can complement cytology as an additional useful technique for detection of bladder carcinoma.

Original language	English (US)
Pages (from-to)	68-71
Number of pages	4
Journal	Urology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/0090-4295(81)90499-4
State	Published - Jul 1981

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Urology

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Nissenkorn, I., McCallum, L., Crabtree, W. N., Murphy, W. M., & Soloway, M. S. (1981). Evaluation of cystography for detection of bladder carcinoma in mice Comparison with Urinary Cytology. Urology, 18(1), 68-71. https://doi.org/10.1016/0090-4295(81)90499-4

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10.1016/0090-4295(81)90499-4