Evaluation of cystography for detection of bladder carcinoma in mice Comparison with Urinary Cytology

Israel Nissenkorn, Lee McCallum, William N. Crabtree, William M. Murphy, Mark S. Soloway

Research output: Contribution to journalArticle

Abstract

Cystography was compared to urinary cytology in an effort to determine whether or not this modality might be useful in the detection of FANFT-induced bladder tumors in mice. Compared to gross examination of the bladders in 24 mice, cystography had the same degree of accuracy as urinary cytology - 79.2 per cent. Comparison of the cystographic and cytologic diagnoses with histology revealed that cytology was more accurate, 79.2 vs 66.6 per cent. Cystography was especially helpful in detecting papillary tumors while cytology was more accurate in the detection of high-grade, high-stage tumors or carcinoma in situ (CIS). Cystography in mice can complement cytology as an additional useful technique for detection of bladder carcinoma.

Original languageEnglish (US)
Pages (from-to)68-71
Number of pages4
JournalUrology
Volume18
Issue number1
DOIs
StatePublished - Jul 1981

ASJC Scopus subject areas

  • Urology

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    Nissenkorn, I., McCallum, L., Crabtree, W. N., Murphy, W. M., & Soloway, M. S. (1981). Evaluation of cystography for detection of bladder carcinoma in mice Comparison with Urinary Cytology. Urology, 18(1), 68-71. https://doi.org/10.1016/0090-4295(81)90499-4