TY - JOUR
T1 - Evaluation and treatment of infertile women with Asherman syndrome
T2 - an updated review focusing on the role of hysteroscopy
AU - Di Guardo, Federica
AU - Della Corte, Luigi
AU - Vilos, George Angelos
AU - Carugno, Jose
AU - Török, Péter
AU - Giampaolino, Pierluigi
AU - Manchanda, Rahul
AU - Vitale, Salvatore Giovanni
N1 - Publisher Copyright:
© 2020 Reproductive Healthcare Ltd.
PY - 2020/7
Y1 - 2020/7
N2 - Asherman syndrome is a rare acquired clinical condition resulting in the obliteration of the uterine cavity causedby the presence of partial or complete fibrous intrauterine adhesions involving at least two-thirds of the uterine cavity potentially obstructing the internal cervical orifice. Common reported symptoms of the disease are alterations of the menstrual pattern with decreased menstrual bleeding leading up to amenorrhoea and infertility. Hysteroscopy is currently considered the gold standard diagnostic and therapeutic approach for patients with intrauterine adhesions. An integrated approach, including preoperative, intraoperative and postoperative therapeutic measures, however, are warranted owing to the complexity of the syndrome. This review aims to summarize the most recent evidence on the recommended preoperative, intraoperative and postoperative procedures to restore the uterine cavity and a functional endometrium, as well as on the concomitant use of adjuvant therapies to achieve optimal fertility outcomes.
AB - Asherman syndrome is a rare acquired clinical condition resulting in the obliteration of the uterine cavity causedby the presence of partial or complete fibrous intrauterine adhesions involving at least two-thirds of the uterine cavity potentially obstructing the internal cervical orifice. Common reported symptoms of the disease are alterations of the menstrual pattern with decreased menstrual bleeding leading up to amenorrhoea and infertility. Hysteroscopy is currently considered the gold standard diagnostic and therapeutic approach for patients with intrauterine adhesions. An integrated approach, including preoperative, intraoperative and postoperative therapeutic measures, however, are warranted owing to the complexity of the syndrome. This review aims to summarize the most recent evidence on the recommended preoperative, intraoperative and postoperative procedures to restore the uterine cavity and a functional endometrium, as well as on the concomitant use of adjuvant therapies to achieve optimal fertility outcomes.
KW - Asherman's syndrome
KW - Hysteroscopy
KW - Infertility
KW - Intrauterine adhesions
KW - Synechiae
UR - http://www.scopus.com/inward/record.url?scp=85084861058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85084861058&partnerID=8YFLogxK
U2 - 10.1016/j.rbmo.2020.03.021
DO - 10.1016/j.rbmo.2020.03.021
M3 - Review article
C2 - 32444259
AN - SCOPUS:85084861058
VL - 41
SP - 55
EP - 61
JO - Reproductive BioMedicine Online
JF - Reproductive BioMedicine Online
SN - 1472-6483
IS - 1
ER -