Evaluating the bleeding neonate

Research output: Contribution to journalArticle

Abstract

Neonatal bleeding disorders must be diagnosed and coagulation studies interpreted in light of the known neonatal hemostatic deficits. The evaluation should begin with a complete history of family and maternal illness, drug ingestion, and complications during gestation, labor and delivery. Confirmation of vitamin K administration is essential. Physical examination should reveal whether or not the infant is healthy or systemically ill. Bleeding in healthy infants is usually due to vitamin K deficiency, immune-mediated thrombocytopenia, coagulation factor deficits, and local problems secondary to birth trauma. Sick infants are more likely to have bleeding associated with disseminated intravascular coagulation, mechanical consumption of platelets (sepsis, necrotizing enterocolitis, etc.), or hepatic dysfunction. Initial coagulation screen should include platelet count, PT and PTT, with careful attention to potential methodologic errors. Confirmatory tests (thrombin time, fibrin split products, platelet function tests, factor assays, etc.) may be necessary in some cases, but most neonatal bleeding disorders can be readily diagnosed and managed by the outlined approach.

Original languageEnglish (US)
Pages (from-to)73-86
Number of pages14
JournalCritical Care Quarterly
Volume2
Issue number3
StatePublished - Jan 1 1979
Externally publishedYes

Fingerprint

Newborn Infant
Hemorrhage
Platelet Function Tests
Vitamin K Deficiency
Thrombin Time
Necrotizing Enterocolitis
Blood Coagulation Factors
Idiopathic Thrombocytopenic Purpura
Vitamin K
Disseminated Intravascular Coagulation
Hemostatics
Fibrin
Platelet Count
Physical Examination
Sepsis
Blood Platelets
Eating
Mothers
Parturition
Pregnancy

ASJC Scopus subject areas

  • Nursing(all)
  • Critical Care and Intensive Care Medicine

Cite this

Evaluating the bleeding neonate. / Bandstra, Emmalee S.

In: Critical Care Quarterly, Vol. 2, No. 3, 01.01.1979, p. 73-86.

Research output: Contribution to journalArticle

@article{d07776dae23b4077a89dcc7b1ed5e6e3,
title = "Evaluating the bleeding neonate",
abstract = "Neonatal bleeding disorders must be diagnosed and coagulation studies interpreted in light of the known neonatal hemostatic deficits. The evaluation should begin with a complete history of family and maternal illness, drug ingestion, and complications during gestation, labor and delivery. Confirmation of vitamin K administration is essential. Physical examination should reveal whether or not the infant is healthy or systemically ill. Bleeding in healthy infants is usually due to vitamin K deficiency, immune-mediated thrombocytopenia, coagulation factor deficits, and local problems secondary to birth trauma. Sick infants are more likely to have bleeding associated with disseminated intravascular coagulation, mechanical consumption of platelets (sepsis, necrotizing enterocolitis, etc.), or hepatic dysfunction. Initial coagulation screen should include platelet count, PT and PTT, with careful attention to potential methodologic errors. Confirmatory tests (thrombin time, fibrin split products, platelet function tests, factor assays, etc.) may be necessary in some cases, but most neonatal bleeding disorders can be readily diagnosed and managed by the outlined approach.",
author = "Bandstra, {Emmalee S}",
year = "1979",
month = "1",
day = "1",
language = "English (US)",
volume = "2",
pages = "73--86",
journal = "Critical Care Nursing Quarterly",
issn = "0887-9303",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Evaluating the bleeding neonate

AU - Bandstra, Emmalee S

PY - 1979/1/1

Y1 - 1979/1/1

N2 - Neonatal bleeding disorders must be diagnosed and coagulation studies interpreted in light of the known neonatal hemostatic deficits. The evaluation should begin with a complete history of family and maternal illness, drug ingestion, and complications during gestation, labor and delivery. Confirmation of vitamin K administration is essential. Physical examination should reveal whether or not the infant is healthy or systemically ill. Bleeding in healthy infants is usually due to vitamin K deficiency, immune-mediated thrombocytopenia, coagulation factor deficits, and local problems secondary to birth trauma. Sick infants are more likely to have bleeding associated with disseminated intravascular coagulation, mechanical consumption of platelets (sepsis, necrotizing enterocolitis, etc.), or hepatic dysfunction. Initial coagulation screen should include platelet count, PT and PTT, with careful attention to potential methodologic errors. Confirmatory tests (thrombin time, fibrin split products, platelet function tests, factor assays, etc.) may be necessary in some cases, but most neonatal bleeding disorders can be readily diagnosed and managed by the outlined approach.

AB - Neonatal bleeding disorders must be diagnosed and coagulation studies interpreted in light of the known neonatal hemostatic deficits. The evaluation should begin with a complete history of family and maternal illness, drug ingestion, and complications during gestation, labor and delivery. Confirmation of vitamin K administration is essential. Physical examination should reveal whether or not the infant is healthy or systemically ill. Bleeding in healthy infants is usually due to vitamin K deficiency, immune-mediated thrombocytopenia, coagulation factor deficits, and local problems secondary to birth trauma. Sick infants are more likely to have bleeding associated with disseminated intravascular coagulation, mechanical consumption of platelets (sepsis, necrotizing enterocolitis, etc.), or hepatic dysfunction. Initial coagulation screen should include platelet count, PT and PTT, with careful attention to potential methodologic errors. Confirmatory tests (thrombin time, fibrin split products, platelet function tests, factor assays, etc.) may be necessary in some cases, but most neonatal bleeding disorders can be readily diagnosed and managed by the outlined approach.

UR - http://www.scopus.com/inward/record.url?scp=0018574918&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018574918&partnerID=8YFLogxK

M3 - Article

VL - 2

SP - 73

EP - 86

JO - Critical Care Nursing Quarterly

JF - Critical Care Nursing Quarterly

SN - 0887-9303

IS - 3

ER -