Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: A population-based study

Felix M. Chinea, Vivek N. Patel, Deukwoo Kwon, Narottam Lamichhane, Chris Lopez, Sanoj Punnen, Erin N. Kobetz, Matthew C. Abramowitz, Alan Pollack

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Background: Few studies focus on prostate cancer (PCa) outcomes in Hispanic/Latino men. Our study explores whether Hispanic/Latino subgroups demonstrate significantly different prostate cancer-specific mortality (PCSM) relative to Non-Hispanic White (NHW) and Non-Hispanic Black (NHB) men. Methods: We extracted a population-based cohort of men diagnosed with local-regional PCa from 2000-2013 (n= 486,865). PCSM was measured in racial/ethnic groups: NHW (n=352,886), NHB (n= 70,983), Hispanic/Latino (n= 40,462), and Asian American/Pacific Islander (n= 22,534). PCSM was also measured in Hispanic/Latino subgroups: Mexican (n= 8,077), Puerto Rican (n= 1,284), South or Central American (n= 3,021), Cuban (n= 788), and Dominican (n= 300). We conducted univariable and multivariable analyses (MVA) to compare risk for PCSM. Results: Compared to NHW men, results showed worse outcomes for NHB men with similar outcomes for Hispanic/Latino men. In MVA with NHW men as a reference, NHB (HR= 1.15, p < 0.001) men had significantly worse PCSM and Hispanic/Latino (HR= 1.02, p= 0.534) men did not show a significant difference. In a second MVA, Puerto Rican (HR= 1.71, p < 0.001) and Mexican (HR= 1.21, p= 0.008) men had significantly higher PCSM. With NHB men as a reference, the MVA showed Puerto Rican (HR= 1.50, p= 0.006) men with higher PCSM and Mexican (HR= 1.08, p= 0.307) men with no significant difference. Conclusions: Our findings indicate previously unknown disparities in PCSM for Puerto Rican and Mexican American men.

Original languageEnglish (US)
Pages (from-to)69709-69721
Number of pages13
Issue number41
StatePublished - 2017


  • Cancer specific mortality
  • Health disparities
  • Hispanic/Latino
  • Minority health
  • Prostate cancer

ASJC Scopus subject areas

  • Oncology


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