Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

Brian A. Naughton, David J. Birnbach, Philip Liu, Gail A. Kolks, Ming Z. Tung, Sam J. Piliero, Albert S. Gordon

Research output: Contribution to journalArticle

5 Scopus citations


Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

Original languageEnglish (US)
Pages (from-to)170-174
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number2
StatePublished - Feb 1979
Externally publishedYes


ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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