Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

Brian A. Naughton; David J. Birnbach; Philip Liu; Gail A. Kolks; Ming Z. Tung; Sam J. Piliero; Albert S. Gordon

doi:10.3181/00379727-160-40413

Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

Brian A. Naughton, David J. Birnbach, Philip Liu, Gail A. Kolks, Ming Z. Tung, Sam J. Piliero, Albert S. Gordon

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

Original language	English (US)
Pages (from-to)	170-174
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	160
Issue number	2
DOIs	https://doi.org/10.3181/00379727-160-40413
State	Published - Feb 1979
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.3181/00379727-160-40413

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Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia. / Naughton, Brian A.; Birnbach, David J.; Liu, Philip; Kolks, Gail A.; Tung, Ming Z.; Piliero, Sam J.; Gordon, Albert S.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 160, No. 2, 02.1979, p. 170-174.

Research output: Contribution to journal › Article

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abstract = "Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.",

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AU - Gordon, Albert S.

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