Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

Brian A. Naughton; David J. Birnbach; Philip Liu; Gail A. Kolks; Ming Z. Tung; Sam J. Piliero; Albert S. Gordon

doi:10.3181/00379727-160-40413

Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

Brian A. Naughton, David J. Birnbach, Philip Liu, Gail A. Kolks, Ming Z. Tung, Sam J. Piliero, Albert S. Gordon

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

Original language	English (US)
Pages (from-to)	170-174
Number of pages	5
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	160
Issue number	2
DOIs	https://doi.org/10.3181/00379727-160-40413
State	Published - Feb 1979
Externally published	Yes

Fingerprint

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Naughton, B. A., Birnbach, D. J., Liu, P., Kolks, G. A., Tung, M. Z., Piliero, S. J., & Gordon, A. S. (1979). Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia. Proceedings of the Society for Experimental Biology and Medicine, 160(2), 170-174. https://doi.org/10.3181/00379727-160-40413

Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia. / Naughton, Brian A.; Birnbach, David J.; Liu, Philip; Kolks, Gail A.; Tung, Ming Z.; Piliero, Sam J.; Gordon, Albert S.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 160, No. 2, 02.1979, p. 170-174.

Research output: Contribution to journal › Article

@article{b9a208ed9bf0460ca8a34d04a4ac93b3,

title = "Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia",

abstract = "Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.",

author = "Naughton, {Brian A.} and Birnbach, {David J.} and Philip Liu and Kolks, {Gail A.} and Tung, {Ming Z.} and Piliero, {Sam J.} and Gordon, {Albert S.}",

year = "1979",

month = feb,

doi = "10.3181/00379727-160-40413",

language = "English (US)",

volume = "160",

pages = "170--174",

journal = "Experimental Biology and Medicine",

issn = "0037-9727",

publisher = "Society for Experimental Biology and Medicine",

number = "2",

}

TY - JOUR

T1 - Erythropoietin (Ep) Production and Kupffer Cell Alterations following Nephrectomy, Hypoxia, or Combined Nephrectomy and Hypoxia

AU - Naughton, Brian A.

AU - Birnbach, David J.

AU - Liu, Philip

AU - Kolks, Gail A.

AU - Tung, Ming Z.

AU - Piliero, Sam J.

AU - Gordon, Albert S.

PY - 1979/2

Y1 - 1979/2

N2 - Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

AB - Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

UR - http://www.scopus.com/inward/record.url?scp=0018742457&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018742457&partnerID=8YFLogxK

U2 - 10.3181/00379727-160-40413

DO - 10.3181/00379727-160-40413

M3 - Article

C2 - 419142

AN - SCOPUS:0018742457

VL - 160

SP - 170

EP - 174

JO - Experimental Biology and Medicine

JF - Experimental Biology and Medicine

SN - 0037-9727

IS - 2

ER -

Access to Document

10.3181/00379727-160-40413