Erythropoietin (Ep) production and Kupffer cell alterations following nephrectomy, hypoxia, or combined nephrectomy and hypoxia

B. A. Naughton, David Birnbach, P. Liu, G. A. Kolks, M. Z. Tung, S. J. Piliero, A. S. Gordon

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Hepatic cells were evaluated using scintillation scanning and counting, autoradiography, and planimetry under conditions favoring extrarenal Ep production. In general, Kupffer cell activity paralleled Ep production whereas the liver parenchymal cells did not manifest significant changes. The studies suggest that the Kupffer cell may be an extrarenal cellular site of Ep production.

Original languageEnglish
Pages (from-to)170-174
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume160
Issue number2
StatePublished - Dec 1 1979
Externally publishedYes

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Kupffer Cells
Erythropoietin
Nephrectomy
Scintillation Counting
Scintillation
Autoradiography
Liver
Hepatocytes
Scanning
Hypoxia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Erythropoietin (Ep) production and Kupffer cell alterations following nephrectomy, hypoxia, or combined nephrectomy and hypoxia. / Naughton, B. A.; Birnbach, David; Liu, P.; Kolks, G. A.; Tung, M. Z.; Piliero, S. J.; Gordon, A. S.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 160, No. 2, 01.12.1979, p. 170-174.

Research output: Contribution to journalArticle

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