Studies of erythroeytic indices and osmotic response revealed the presence of 2 abnormal populations of cells in hamsters infected with Plasmodium bergkei. One population consisted of mature nonpar asitized cells which became abnormally small and spherocytic with a diminished cellular surface area. This cell shrinkage could result from the hypersplenism of malaria or possibly from immunologic membrane damage. The other population was composed of parasitized re-ticulocytes which exhibited an increased rate of swelling in hypotonic saline, indicating impairment of the normal restricted cation permeability.
|Original language||English (US)|
|Number of pages||5|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Apr 1967|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)