Abstract
Studies of erythroeytic indices and osmotic response revealed the presence of 2 abnormal populations of cells in hamsters infected with Plasmodium bergkei. One population consisted of mature nonpar asitized cells which became abnormally small and spherocytic with a diminished cellular surface area. This cell shrinkage could result from the hypersplenism of malaria or possibly from immunologic membrane damage. The other population was composed of parasitized re-ticulocytes which exhibited an increased rate of swelling in hypotonic saline, indicating impairment of the normal restricted cation permeability.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1086-1090 |
| Number of pages | 5 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 124 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1967 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Cite this
George, J. N., Wicker, D. J., Fogel, B. J., Shields, C. E., & Conrad, M. E. (1967). Erythrocytic Abnormalities in Experimental Malaria. Proceedings of the Society for Experimental Biology and Medicine, 124(4), 1086-1090. https://doi.org/10.3181/00379727-124-31931