Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

Rajinder Dawra, O. P. Sharma, L. Krishna, J. Vaid

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

Original languageEnglish (US)
Pages (from-to)143-146
Number of pages4
JournalCancer Letters
Volume48
Issue number2
DOIs
StatePublished - Nov 30 1989
Externally publishedYes

Fingerprint

Urinary Bladder Neoplasms
Peroxidase
Glutathione
Pteridium
Erythrocytes
Hematuria
Enzymes
Transferases
Oxidoreductases
Oxygen
Wounds and Injuries

Keywords

  • bovine urinary bladder cancer
  • enzootic bovine hematuria
  • erythrocytes
  • glutathione
  • glutathione peroxidase

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer. / Dawra, Rajinder; Sharma, O. P.; Krishna, L.; Vaid, J.

In: Cancer Letters, Vol. 48, No. 2, 30.11.1989, p. 143-146.

Research output: Contribution to journalArticle

Dawra, Rajinder ; Sharma, O. P. ; Krishna, L. ; Vaid, J. / Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer. In: Cancer Letters. 1989 ; Vol. 48, No. 2. pp. 143-146.
@article{44bf6a7a4ed14c2fa02864c56131947c,
title = "Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer",
abstract = "Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.",
keywords = "bovine urinary bladder cancer, enzootic bovine hematuria, erythrocytes, glutathione, glutathione peroxidase",
author = "Rajinder Dawra and Sharma, {O. P.} and L. Krishna and J. Vaid",
year = "1989",
month = "11",
day = "30",
doi = "10.1016/0304-3835(89)90051-7",
language = "English (US)",
volume = "48",
pages = "143--146",
journal = "Cancer Letters",
issn = "0304-3835",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

AU - Dawra, Rajinder

AU - Sharma, O. P.

AU - Krishna, L.

AU - Vaid, J.

PY - 1989/11/30

Y1 - 1989/11/30

N2 - Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

AB - Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

KW - bovine urinary bladder cancer

KW - enzootic bovine hematuria

KW - erythrocytes

KW - glutathione

KW - glutathione peroxidase

UR - http://www.scopus.com/inward/record.url?scp=0024472102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024472102&partnerID=8YFLogxK

U2 - 10.1016/0304-3835(89)90051-7

DO - 10.1016/0304-3835(89)90051-7

M3 - Article

C2 - 2819701

AN - SCOPUS:0024472102

VL - 48

SP - 143

EP - 146

JO - Cancer Letters

JF - Cancer Letters

SN - 0304-3835

IS - 2

ER -