Erythrocyte glutathione and its metabolizing enzymes in bovine urinary bladder cancer

R. K. Dawra, O. P. Sharma, L. Krishna, J. Vaid

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Glutathione and its metabolizing enzymes were studied in erythrocytes of cattle suffering from urinary bladder cancer and associated hematuria. The concentration of glutathione (GSH) and GSH peroxidase activity were subnormal in the affected animals, whereas activities of GSH reductase and GSH S-transferase were not altered. Decreased GSH and GSH peroxidase are likely to make erythrocytes of the affected animals more susceptible to oxygen-induced injury and the radiomimetic effect of bracken fern.

Original languageEnglish (US)
Pages (from-to)143-146
Number of pages4
JournalCancer letters
Volume48
Issue number2
DOIs
StatePublished - Nov 30 1989
Externally publishedYes

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Keywords

  • bovine urinary bladder cancer
  • enzootic bovine hematuria
  • erythrocytes
  • glutathione
  • glutathione peroxidase

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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