Erythrocyte choline concentrations are elevated in manic patients

Richard S Jope, D. J. Jenden, B. E. Ehrlich, J. M. Diamond, L. F. Gosenfeld

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The intracellular choline concentration in erythrocytes of manic patients who never had lithium therapy was 3 times the value for normal human subjects. Lithium therapy increased this value to 11 times normal, and the increase began within the first 2 days of lithium therapy. Plasma choline concentration was normal in untreated manic patients and did not change during lithium therapy.

Original languageEnglish
Pages (from-to)6144-6146
Number of pages3
JournalProceedings of the National Academy of Sciences of the United States of America
Volume77
Issue number10 II
DOIs
StatePublished - Dec 1 1980
Externally publishedYes

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Choline
Lithium
Erythrocytes
Therapeutics
Reference Values

ASJC Scopus subject areas

  • Genetics
  • General

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Erythrocyte choline concentrations are elevated in manic patients. / Jope, Richard S; Jenden, D. J.; Ehrlich, B. E.; Diamond, J. M.; Gosenfeld, L. F.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 77, No. 10 II, 01.12.1980, p. 6144-6146.

Research output: Contribution to journalArticle

Jope, Richard S ; Jenden, D. J. ; Ehrlich, B. E. ; Diamond, J. M. ; Gosenfeld, L. F. / Erythrocyte choline concentrations are elevated in manic patients. In: Proceedings of the National Academy of Sciences of the United States of America. 1980 ; Vol. 77, No. 10 II. pp. 6144-6146.
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