Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula

Kris Ghosh, Melissa A. Geller, Leo B. Twiggs

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background. With the pharmacokinetic advantages of intraperitoneal chemotherapy delivery and the increased popularity of immunotherapy and gene therapy, intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. This delivery system, however, carries with it an intrinsic morbidity warranting attention in the often prolonged chemotherapy regimens demanded by cancer patients. Case. In reviewing the literature of intraperitoneal catheter complications, there is no other cited case of a peritoneal catheter erosion into intestine presenting as an enterovaginal fistula. Our patient, diagnosed with persistent ovarian carcinoma, had a peritoneal Tenckoff catheter placed for chemotherapy. Many months after termination of the chemotherapy and 15 months after placement, she presented with bowel contents per vagina. A CT scan revealed an abdominopelvic abscess encompassing the detached catheter which embedded in the rectosigmoid colon, allowing direct communication to the upper vagina. The catheter was removed and the abscess was drained. Conclusion. Intraperitoneal catheters have a morbidity that persists after nonuse. Therefore, intraperitoneal catheters should be removed if they are not being used. (C) 2000 Academic Press.

Original languageEnglish
Pages (from-to)327-329
Number of pages3
JournalGynecologic Oncology
Volume77
Issue number2
DOIs
StatePublished - May 1 2000
Externally publishedYes

Fingerprint

Fistula
Catheters
Drug Therapy
Vagina
Abscess
Morbidity
Genetic Therapy
Immunotherapy
Intestines
Neoplasms
Colon
Pharmacokinetics
Communication
Carcinoma

Keywords

  • Complications
  • Enterovaginal fistulas
  • Intraperitoneal port-a-caths

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula. / Ghosh, Kris; Geller, Melissa A.; Twiggs, Leo B.

In: Gynecologic Oncology, Vol. 77, No. 2, 01.05.2000, p. 327-329.

Research output: Contribution to journalArticle

Ghosh, Kris ; Geller, Melissa A. ; Twiggs, Leo B. / Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula. In: Gynecologic Oncology. 2000 ; Vol. 77, No. 2. pp. 327-329.
@article{132cb75f798e4c5e8b555c0a7473ec80,
title = "Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula",
abstract = "Background. With the pharmacokinetic advantages of intraperitoneal chemotherapy delivery and the increased popularity of immunotherapy and gene therapy, intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. This delivery system, however, carries with it an intrinsic morbidity warranting attention in the often prolonged chemotherapy regimens demanded by cancer patients. Case. In reviewing the literature of intraperitoneal catheter complications, there is no other cited case of a peritoneal catheter erosion into intestine presenting as an enterovaginal fistula. Our patient, diagnosed with persistent ovarian carcinoma, had a peritoneal Tenckoff catheter placed for chemotherapy. Many months after termination of the chemotherapy and 15 months after placement, she presented with bowel contents per vagina. A CT scan revealed an abdominopelvic abscess encompassing the detached catheter which embedded in the rectosigmoid colon, allowing direct communication to the upper vagina. The catheter was removed and the abscess was drained. Conclusion. Intraperitoneal catheters have a morbidity that persists after nonuse. Therefore, intraperitoneal catheters should be removed if they are not being used. (C) 2000 Academic Press.",
keywords = "Complications, Enterovaginal fistulas, Intraperitoneal port-a-caths",
author = "Kris Ghosh and Geller, {Melissa A.} and Twiggs, {Leo B.}",
year = "2000",
month = "5",
day = "1",
doi = "10.1006/gyno.2000.5792",
language = "English",
volume = "77",
pages = "327--329",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Erosion of an intraperitoneal chemotherapy catheter resulting in an enterovaginal fistula

AU - Ghosh, Kris

AU - Geller, Melissa A.

AU - Twiggs, Leo B.

PY - 2000/5/1

Y1 - 2000/5/1

N2 - Background. With the pharmacokinetic advantages of intraperitoneal chemotherapy delivery and the increased popularity of immunotherapy and gene therapy, intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. This delivery system, however, carries with it an intrinsic morbidity warranting attention in the often prolonged chemotherapy regimens demanded by cancer patients. Case. In reviewing the literature of intraperitoneal catheter complications, there is no other cited case of a peritoneal catheter erosion into intestine presenting as an enterovaginal fistula. Our patient, diagnosed with persistent ovarian carcinoma, had a peritoneal Tenckoff catheter placed for chemotherapy. Many months after termination of the chemotherapy and 15 months after placement, she presented with bowel contents per vagina. A CT scan revealed an abdominopelvic abscess encompassing the detached catheter which embedded in the rectosigmoid colon, allowing direct communication to the upper vagina. The catheter was removed and the abscess was drained. Conclusion. Intraperitoneal catheters have a morbidity that persists after nonuse. Therefore, intraperitoneal catheters should be removed if they are not being used. (C) 2000 Academic Press.

AB - Background. With the pharmacokinetic advantages of intraperitoneal chemotherapy delivery and the increased popularity of immunotherapy and gene therapy, intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. This delivery system, however, carries with it an intrinsic morbidity warranting attention in the often prolonged chemotherapy regimens demanded by cancer patients. Case. In reviewing the literature of intraperitoneal catheter complications, there is no other cited case of a peritoneal catheter erosion into intestine presenting as an enterovaginal fistula. Our patient, diagnosed with persistent ovarian carcinoma, had a peritoneal Tenckoff catheter placed for chemotherapy. Many months after termination of the chemotherapy and 15 months after placement, she presented with bowel contents per vagina. A CT scan revealed an abdominopelvic abscess encompassing the detached catheter which embedded in the rectosigmoid colon, allowing direct communication to the upper vagina. The catheter was removed and the abscess was drained. Conclusion. Intraperitoneal catheters have a morbidity that persists after nonuse. Therefore, intraperitoneal catheters should be removed if they are not being used. (C) 2000 Academic Press.

KW - Complications

KW - Enterovaginal fistulas

KW - Intraperitoneal port-a-caths

UR - http://www.scopus.com/inward/record.url?scp=0034125565&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034125565&partnerID=8YFLogxK

U2 - 10.1006/gyno.2000.5792

DO - 10.1006/gyno.2000.5792

M3 - Article

C2 - 10785489

AN - SCOPUS:0034125565

VL - 77

SP - 327

EP - 329

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 2

ER -