Abstract
Epithelioid sarcoma is an uncommon malignancy that usually arises in the superficial soft tissues of the extremities. Classically, epithelioid sarcoma grows as nodules of mild to moderately atypical epithelioid cells, frequently with central necrosis. The stroma is variably fibrous and may rarely contain heterotopic bone. The presence of bone within epithelioid sarcoma raises a variety of lesions in the differential diagnosis, including reactive processes as well as benign and malignant neoplasms.This morphological variant of epithelioid sarcoma and its associated diagnostic pitfalls has received little attention in the literature. The authors report herein 4 cases of epithelioid sarcoma with heterotopic bone and highlight the morphological characteristics of the bone and how such variants can be distinguished from other bone-forming lesions of the soft tissues.
| Original language | English |
|---|---|
| Pages (from-to) | 207-212 |
| Number of pages | 6 |
| Journal | International Journal of Surgical Pathology |
| Volume | 18 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 2010 |
| Externally published | Yes |
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Keywords
- Epithelioid sarcoma
- Heterotopic bone
ASJC Scopus subject areas
- Anatomy
- Pathology and Forensic Medicine
- Surgery
Cite this
Epithelioid sarcoma with heterotopic bone : A morphologic review of 4 cases. / Koplin, Stephanie A.; Petur Nielsen, G.; Hornicek, Francis J.; Rosenberg, Andrew.
In: International Journal of Surgical Pathology, Vol. 18, No. 3, 01.06.2010, p. 207-212.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epithelioid sarcoma with heterotopic bone
T2 - A morphologic review of 4 cases
AU - Koplin, Stephanie A.
AU - Petur Nielsen, G.
AU - Hornicek, Francis J.
AU - Rosenberg, Andrew
PY - 2010/6/1
Y1 - 2010/6/1
N2 - Epithelioid sarcoma is an uncommon malignancy that usually arises in the superficial soft tissues of the extremities. Classically, epithelioid sarcoma grows as nodules of mild to moderately atypical epithelioid cells, frequently with central necrosis. The stroma is variably fibrous and may rarely contain heterotopic bone. The presence of bone within epithelioid sarcoma raises a variety of lesions in the differential diagnosis, including reactive processes as well as benign and malignant neoplasms.This morphological variant of epithelioid sarcoma and its associated diagnostic pitfalls has received little attention in the literature. The authors report herein 4 cases of epithelioid sarcoma with heterotopic bone and highlight the morphological characteristics of the bone and how such variants can be distinguished from other bone-forming lesions of the soft tissues.
AB - Epithelioid sarcoma is an uncommon malignancy that usually arises in the superficial soft tissues of the extremities. Classically, epithelioid sarcoma grows as nodules of mild to moderately atypical epithelioid cells, frequently with central necrosis. The stroma is variably fibrous and may rarely contain heterotopic bone. The presence of bone within epithelioid sarcoma raises a variety of lesions in the differential diagnosis, including reactive processes as well as benign and malignant neoplasms.This morphological variant of epithelioid sarcoma and its associated diagnostic pitfalls has received little attention in the literature. The authors report herein 4 cases of epithelioid sarcoma with heterotopic bone and highlight the morphological characteristics of the bone and how such variants can be distinguished from other bone-forming lesions of the soft tissues.
KW - Epithelioid sarcoma
KW - Heterotopic bone
UR - http://www.scopus.com/inward/record.url?scp=77952274414&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952274414&partnerID=8YFLogxK
U2 - 10.1177/1066896909352862
DO - 10.1177/1066896909352862
M3 - Article
C2 - 20034988
AN - SCOPUS:77952274414
VL - 18
SP - 207
EP - 212
JO - International Journal of Surgical Pathology
JF - International Journal of Surgical Pathology
SN - 1066-8969
IS - 3
ER -