Epithelial ingrowth in the flap-graft interface after microkeratome-assisted posterior penetrating keratoplasty

Victor L. Perez, Kathryn A. Colby, Dimitri T. Azar

Research output: Contribution to journalArticle

7 Scopus citations


A 79-year-old woman with pseudophakic bullous keratopathy had microkeratome-assisted posterior keratoplasty for the treatment of clinically significant corneal edema. An island of epithelial ingrowth was noted in the flap-graft interface that was not communicating with the flap periphery. Partial lifting of the anterior corneal flap and removal and irrigation of the epithelial cells were successfully performed. A review of reports of microkeratome-assisted posterior penetrating keratoplasty shows epithelial ingrowth is common after this procedure. The presence of posterior sutures, a central location of the epithelial cells, communication with the periphery, and evidence of stromal melting should prompt immediate surgical intervention.

Original languageEnglish (US)
Pages (from-to)2225-2228
Number of pages4
JournalJournal of cataract and refractive surgery
Issue number11
StatePublished - Nov 2003


ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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