Epithelial breakthrough during IntraLase flap creation for laser in situ keratomileusis

Michael I. Seider, Takeshi Ide, George D. Kymionis, William W. Culbertson, Terrence P. O'Brien, Sonia H. Yoo

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


We report the clinical manifestations and outcomes in 4 patients who experienced premature gas-bubble leakage during raster lamellar dissection during IntraLase femtosecond laser corneal flap creation. Three patients experienced a full-thickness epithelial breakthrough and the fourth, a flap tear. The patient who experienced the flap tear was unable to have laser in situ keratomileusis successfully. The flap complications did not result in a decreased best corrected visual acuity in any patient but may have resulted in epithelial ingrowth in one and a corneal scar and microstriae in another. Potential predisposing factors for epithelial breakthrough, the incidence of epithelial breakthrough, and methods for avoiding and salvaging traumatic corneal flaps are discussed.

Original languageEnglish (US)
Pages (from-to)859-863
Number of pages5
JournalJournal of cataract and refractive surgery
Issue number5
StatePublished - May 2008

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems


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