Epilepsy, surgery, and the elderly

Bruno V. Gallo

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Treatment of elderly patients with epilepsy may present unique challenges to physicians. Co-morbid conditions and drugs to treat such conditions are common in elderly patients, possibly complicating epilepsy therapies that are dependent on drugs alone. For this reason, surgical intervention may be an attractive option for elderly patients with epilepsy, particularly for medically intractable patients with key disease features, such as lateralization and precisely localized epileptic foci. Curative procedures, including lobectomy and lesionectomy, are most likely to lead to seizure freedom, but not all patients are candidates for such procedures. When a curative surgical procedure is not an option, palliative procedures, including vagus nerve stimulation and deep brain stimulation, may be viable options. Vagus nerve stimulation has been reported to reduce seizure rates and improve quality of life in elderly patients with epilepsy. Currently, widespread therapeutic application of deep brain stimulation is limited by risks, costs, and pending studies.

Original languageEnglish (US)
Pages (from-to)83-86
Number of pages4
JournalEpilepsy Research
Volume68
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 2006

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Keywords

  • Aging brain
  • Clinical trials
  • Elderly
  • Epilepsy
  • Geriatric
  • PK

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

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