Epilepsy, Psychiatric Comorbidities of

Andres M Kanner, A. R. Balabanov

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Psychiatric comorbidities are relatively frequent in patients with epilepsy (PWE), with lifetime prevalence rates ranging between 30% and 35%. Mood and anxiety disorders are the most frequently recognized conditions in adults whereas attention-deficit hyperactivity disorder (ADHD) is the most frequently identified comorbidity in children.Psychiatric disorders have been typically considered to reflect a complication of the seizure disorder. Yet, population-based studies have also demonstrated that patients with a primary psychiatric disorder are at an increased risk of developing epilepsy. Furthermore, the presence of psychiatric comorbidities, preceding the onset of epilepsy has been associated with an increased risk of developing treatment-resistant epilepsy with antiepileptic drugs (AEDs), and a lifetime history of depression has been associated with a lower likelihood to achieve complete seizure freedom in intractable patients who undergo a temporal lobectomy. In addition, psychiatric comorbidities have been associated with a worse tolerance to AEDs, an increased suicidal risk, and a worse quality of life.Thus, an early recognition of psychiatric disorders in PWE is of the essence to ensure a timely treatment and avert these complications.

Original languageEnglish (US)
Title of host publicationEncyclopedia of the Neurological Sciences
PublisherElsevier Inc.
Pages147-151
Number of pages5
ISBN (Electronic)9780123851574
ISBN (Print)9780123851581
DOIs
StatePublished - Jan 1 2014

Fingerprint

Psychiatry
Comorbidity
Epilepsy
Anticonvulsants
Attention Deficit Disorder with Hyperactivity
Anxiety Disorders
Mood Disorders
Seizures
Quality of Life
Depression
Therapeutics
Population

Keywords

  • Attention-deficit hyperactivity disorder
  • Generalized anxiety disorder
  • Interictal dysphoric disorder
  • Major depressive disorders
  • Panic disorder
  • Phobias
  • Psychosis of epilepsy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kanner, A. M., & Balabanov, A. R. (2014). Epilepsy, Psychiatric Comorbidities of. In Encyclopedia of the Neurological Sciences (pp. 147-151). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-385157-4.00299-2

Epilepsy, Psychiatric Comorbidities of. / Kanner, Andres M; Balabanov, A. R.

Encyclopedia of the Neurological Sciences. Elsevier Inc., 2014. p. 147-151.

Research output: Chapter in Book/Report/Conference proceedingChapter

Kanner, AM & Balabanov, AR 2014, Epilepsy, Psychiatric Comorbidities of. in Encyclopedia of the Neurological Sciences. Elsevier Inc., pp. 147-151. https://doi.org/10.1016/B978-0-12-385157-4.00299-2
Kanner AM, Balabanov AR. Epilepsy, Psychiatric Comorbidities of. In Encyclopedia of the Neurological Sciences. Elsevier Inc. 2014. p. 147-151 https://doi.org/10.1016/B978-0-12-385157-4.00299-2
Kanner, Andres M ; Balabanov, A. R. / Epilepsy, Psychiatric Comorbidities of. Encyclopedia of the Neurological Sciences. Elsevier Inc., 2014. pp. 147-151
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