Epilepsy and the Ketogenic diet

T. J. Resnick, P. Gennaro, M. S. Duchowny, J. Gilman, L. A. Alvarez, P. Jayakar, P. Dean

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The Ketogenic diet was developed in the early 1900s as a treatment for epilepsy. The diet is a calculated ratio of high-fat to low-carbohydrate/protein components which results in ketonemia and improved seizure control. This high-fat diet was based on a hypothesis that if the brain was deprived of glucose for its prime energy source and utilized ketone bodies instead, an antiepileptic effect would be maintained as long as ketone bodies were the only available energy source. The success of the Ketogenic diet is contingent upon comprehensive parent education and a resource team including a neurologist, a nurse, and a dietitian specifically trained in the diet. Younger children appear to respond more favorably to the diet, probably because it is easier to induce ketosis. Retrospective studies suggest a gratifying reduction of seizures in approximately one-third of patients.

Original languageEnglish
Pages (from-to)102-105
Number of pages4
JournalInternational Pediatrics
Volume12
Issue number2
StatePublished - Dec 1 1997

Fingerprint

Ketogenic Diet
Epilepsy
Ketone Bodies
Ketosis
Diet
Seizures
Nutritionists
High Fat Diet
Anticonvulsants
Retrospective Studies
Fats
Nurses
Carbohydrates
Education
Glucose
Brain
Proteins
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Resnick, T. J., Gennaro, P., Duchowny, M. S., Gilman, J., Alvarez, L. A., Jayakar, P., & Dean, P. (1997). Epilepsy and the Ketogenic diet. International Pediatrics, 12(2), 102-105.

Epilepsy and the Ketogenic diet. / Resnick, T. J.; Gennaro, P.; Duchowny, M. S.; Gilman, J.; Alvarez, L. A.; Jayakar, P.; Dean, P.

In: International Pediatrics, Vol. 12, No. 2, 01.12.1997, p. 102-105.

Research output: Contribution to journalArticle

Resnick, TJ, Gennaro, P, Duchowny, MS, Gilman, J, Alvarez, LA, Jayakar, P & Dean, P 1997, 'Epilepsy and the Ketogenic diet', International Pediatrics, vol. 12, no. 2, pp. 102-105.
Resnick TJ, Gennaro P, Duchowny MS, Gilman J, Alvarez LA, Jayakar P et al. Epilepsy and the Ketogenic diet. International Pediatrics. 1997 Dec 1;12(2):102-105.
Resnick, T. J. ; Gennaro, P. ; Duchowny, M. S. ; Gilman, J. ; Alvarez, L. A. ; Jayakar, P. ; Dean, P. / Epilepsy and the Ketogenic diet. In: International Pediatrics. 1997 ; Vol. 12, No. 2. pp. 102-105.
@article{8bbaff27b6544cc3b9f3e03c4af03d0f,
title = "Epilepsy and the Ketogenic diet",
abstract = "The Ketogenic diet was developed in the early 1900s as a treatment for epilepsy. The diet is a calculated ratio of high-fat to low-carbohydrate/protein components which results in ketonemia and improved seizure control. This high-fat diet was based on a hypothesis that if the brain was deprived of glucose for its prime energy source and utilized ketone bodies instead, an antiepileptic effect would be maintained as long as ketone bodies were the only available energy source. The success of the Ketogenic diet is contingent upon comprehensive parent education and a resource team including a neurologist, a nurse, and a dietitian specifically trained in the diet. Younger children appear to respond more favorably to the diet, probably because it is easier to induce ketosis. Retrospective studies suggest a gratifying reduction of seizures in approximately one-third of patients.",
author = "Resnick, {T. J.} and P. Gennaro and Duchowny, {M. S.} and J. Gilman and Alvarez, {L. A.} and P. Jayakar and P. Dean",
year = "1997",
month = "12",
day = "1",
language = "English",
volume = "12",
pages = "102--105",
journal = "International Pediatrics",
issn = "0885-6265",
publisher = "Miami Children's Hospital Medical Journal Inc.",
number = "2",

}

TY - JOUR

T1 - Epilepsy and the Ketogenic diet

AU - Resnick, T. J.

AU - Gennaro, P.

AU - Duchowny, M. S.

AU - Gilman, J.

AU - Alvarez, L. A.

AU - Jayakar, P.

AU - Dean, P.

PY - 1997/12/1

Y1 - 1997/12/1

N2 - The Ketogenic diet was developed in the early 1900s as a treatment for epilepsy. The diet is a calculated ratio of high-fat to low-carbohydrate/protein components which results in ketonemia and improved seizure control. This high-fat diet was based on a hypothesis that if the brain was deprived of glucose for its prime energy source and utilized ketone bodies instead, an antiepileptic effect would be maintained as long as ketone bodies were the only available energy source. The success of the Ketogenic diet is contingent upon comprehensive parent education and a resource team including a neurologist, a nurse, and a dietitian specifically trained in the diet. Younger children appear to respond more favorably to the diet, probably because it is easier to induce ketosis. Retrospective studies suggest a gratifying reduction of seizures in approximately one-third of patients.

AB - The Ketogenic diet was developed in the early 1900s as a treatment for epilepsy. The diet is a calculated ratio of high-fat to low-carbohydrate/protein components which results in ketonemia and improved seizure control. This high-fat diet was based on a hypothesis that if the brain was deprived of glucose for its prime energy source and utilized ketone bodies instead, an antiepileptic effect would be maintained as long as ketone bodies were the only available energy source. The success of the Ketogenic diet is contingent upon comprehensive parent education and a resource team including a neurologist, a nurse, and a dietitian specifically trained in the diet. Younger children appear to respond more favorably to the diet, probably because it is easier to induce ketosis. Retrospective studies suggest a gratifying reduction of seizures in approximately one-third of patients.

UR - http://www.scopus.com/inward/record.url?scp=0031402610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031402610&partnerID=8YFLogxK

M3 - Article

VL - 12

SP - 102

EP - 105

JO - International Pediatrics

JF - International Pediatrics

SN - 0885-6265

IS - 2

ER -