Epidermoid tumors of the temporal lobe as epileptogenic foci

Simon J. Hanft, Ricardo J. Komotar, Daniel M.S. Raper, Michael B. Sisti, Guy M. McKhann

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Intracerebral epidermoid tumors of the temporal lobe are exceedingly rare. The vast majority of these slow-growing tumors remain clinically silent while only a select few are associated with overt symptomatology. We report two patients with epidermoid tumors whose unique location in the temporal lobe resulted in secondarily generalized seizures. Our first patient, a 19-year-old female, presented with a secondarily generalized tonic-clonic seizure and MRI revealed a superior temporal lobe lesion that was subsequently treated with an awake craniotomy and gross total resection. Our second patient was a 71-year-old male with a recent seizure history and known left temporal lobe lesion. The patient underwent craniotomy for gross total resection of the mass. In these two patients, we found that MRI proved diagnostic and surgical resection was curative. Our clinical experience and review of the literature indicate that gross total resection of these lesions confers control of localization-related epilepsy.

Original languageEnglish (US)
Pages (from-to)1396-1399
Number of pages4
JournalJournal of Clinical Neuroscience
Issue number10
StatePublished - Oct 2011
Externally publishedYes


  • Epidermoid
  • Epilepsy
  • Review
  • Temporal lobe

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)


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