Abstract
The field of epidermal stem cells has dramatically advanced in the last decade, leading to a better understanding of the molecular factors, signalling pathways and cellular events that identify and characterize stem cells, thus revealing their immense potential for therapeutic use. Furthermore, multipotent epidermal stem cells present the major advantage of easy accessibility with the discovery of their specific location within the bulge of the hair follicle. This review focuses on the most recent findings on epidermal stem cells, and their potential role in initial epidermal commitment, differentiation and wound healing processes in the skin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 173-183 |
| Number of pages | 11 |
| Journal | Biology of the Cell |
| Volume | 97 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2005 |
| Externally published | Yes |
Keywords
- Differentiation
- Epidermis
- Hair follicle
- Stem cell
- Wound healing
ASJC Scopus subject areas
- Cell Biology