Abstract
The field of epidermal stem cells has dramatically advanced in the last decade, leading to a better understanding of the molecular factors, signalling pathways and cellular events that identify and characterize stem cells, thus revealing their immense potential for therapeutic use. Furthermore, multipotent epidermal stem cells present the major advantage of easy accessibility with the discovery of their specific location within the bulge of the hair follicle. This review focuses on the most recent findings on epidermal stem cells, and their potential role in initial epidermal commitment, differentiation and wound healing processes in the skin.
| Original language | English |
|---|---|
| Pages (from-to) | 173-183 |
| Number of pages | 11 |
| Journal | Biology of the Cell |
| Volume | 97 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2005 |
| Externally published | Yes |
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Keywords
- Differentiation
- Epidermis
- Hair follicle
- Stem cell
- Wound healing
ASJC Scopus subject areas
- Cell Biology
Cite this
Epidermal stem cells : The cradle of epidermal determination, differentiation and wound healing. / Morasso, Maria I.; Tomic-Canic, Marjana.
In: Biology of the Cell, Vol. 97, No. 3, 01.03.2005, p. 173-183.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epidermal stem cells
T2 - The cradle of epidermal determination, differentiation and wound healing
AU - Morasso, Maria I.
AU - Tomic-Canic, Marjana
PY - 2005/3/1
Y1 - 2005/3/1
N2 - The field of epidermal stem cells has dramatically advanced in the last decade, leading to a better understanding of the molecular factors, signalling pathways and cellular events that identify and characterize stem cells, thus revealing their immense potential for therapeutic use. Furthermore, multipotent epidermal stem cells present the major advantage of easy accessibility with the discovery of their specific location within the bulge of the hair follicle. This review focuses on the most recent findings on epidermal stem cells, and their potential role in initial epidermal commitment, differentiation and wound healing processes in the skin.
AB - The field of epidermal stem cells has dramatically advanced in the last decade, leading to a better understanding of the molecular factors, signalling pathways and cellular events that identify and characterize stem cells, thus revealing their immense potential for therapeutic use. Furthermore, multipotent epidermal stem cells present the major advantage of easy accessibility with the discovery of their specific location within the bulge of the hair follicle. This review focuses on the most recent findings on epidermal stem cells, and their potential role in initial epidermal commitment, differentiation and wound healing processes in the skin.
KW - Differentiation
KW - Epidermis
KW - Hair follicle
KW - Stem cell
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=14944370988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=14944370988&partnerID=8YFLogxK
U2 - 10.1042/BC20040098
DO - 10.1042/BC20040098
M3 - Article
C2 - 15715523
AN - SCOPUS:14944370988
VL - 97
SP - 173
EP - 183
JO - Biology of the Cell
JF - Biology of the Cell
SN - 0248-4900
IS - 3
ER -