Enteric coccidiosis among patients with the acquired immunodeficiency syndrome

M. E. Whiteside, J. S. Barkin, R. G. May, S. D. Weiss, M. A. Fischl, C. L. MacLeod

Research output: Contribution to journalArticle

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Abstract

Ten patients were identified at Jackson Memorial Hospital/University of Miami Hospitals and Clinics with enteric coccidial infection due to Cryptosporidium spp. or Isospora belli. All had the acquired immunodeficiency syndrome as manifested by Kaposi's sarcoma or multiple opportunistic infections, or both. They presented with profuse diarrhea associated with weakness, anorexia, and weight loss. Routine examinations of stools for eggs and parasites as performed by the hospital laboratory were negative in all patients. Sugar flotation and modified acid fast techniques were used in the Tropical Disease Laboratory to identify oocysts of Cryptosporidium spp. in stools of seven patients. Malabsorption, characterized by a low 5-hour D-xylose and positive fecal fat, was observed in 6/6 of these patients. In three other patients Isospora belli oocysts were identified in stool specimens or via a duodenal string test. Spiramycin was the only drug found to be effective in treating patients with cryptosporidiosis. Patients with Isospora belli responded to a prolonged course of trimethoprim-sulfamethoxazole.

Original languageEnglish
Pages (from-to)1065-1072
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume33
Issue number6
StatePublished - Dec 1 1984

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Coccidiosis
Acquired Immunodeficiency Syndrome
Isospora
Cryptosporidium
Oocysts
Spiramycin
Cryptosporidiosis
Hospital Laboratories
Kaposi's Sarcoma
Xylose
Opportunistic Infections
Sulfamethoxazole Drug Combination Trimethoprim
Anorexia
Eggs
Weight Loss
Diarrhea
Parasites
Fats
Acids
Infection

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Enteric coccidiosis among patients with the acquired immunodeficiency syndrome. / Whiteside, M. E.; Barkin, J. S.; May, R. G.; Weiss, S. D.; Fischl, M. A.; MacLeod, C. L.

In: American Journal of Tropical Medicine and Hygiene, Vol. 33, No. 6, 01.12.1984, p. 1065-1072.

Research output: Contribution to journalArticle

Whiteside, M. E. ; Barkin, J. S. ; May, R. G. ; Weiss, S. D. ; Fischl, M. A. ; MacLeod, C. L. / Enteric coccidiosis among patients with the acquired immunodeficiency syndrome. In: American Journal of Tropical Medicine and Hygiene. 1984 ; Vol. 33, No. 6. pp. 1065-1072.
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