Abstract
The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 291-300 |
| Number of pages | 10 |
| Journal | Cancer Genomics and Proteomics |
| Volume | 12 |
| Issue number | 6 |
| State | Published - Nov 1 2015 |
| Externally published | Yes |
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Keywords
- Biobanking
- Biomarker discovery
- ICT tools
- Review
- Sample quality
ASJC Scopus subject areas
- Genetics
- Molecular Biology
- Cancer Research
- Biochemistry
Cite this
Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle. / Riondino, Silvia; Ferroni, Patrizia; Spila, Antonella; Alessandroni, Jhessica; D'Alessandro, Roberta; Formica, Vincenzo; Della Morte, David; Palmirotta, Raffaele; Nanni, Umberto; Roselli, Mario; Guadagni, Fiorella.
In: Cancer Genomics and Proteomics, Vol. 12, No. 6, 01.11.2015, p. 291-300.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle
AU - Riondino, Silvia
AU - Ferroni, Patrizia
AU - Spila, Antonella
AU - Alessandroni, Jhessica
AU - D'Alessandro, Roberta
AU - Formica, Vincenzo
AU - Della Morte, David
AU - Palmirotta, Raffaele
AU - Nanni, Umberto
AU - Roselli, Mario
AU - Guadagni, Fiorella
PY - 2015/11/1
Y1 - 2015/11/1
N2 - The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.
AB - The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.
KW - Biobanking
KW - Biomarker discovery
KW - ICT tools
KW - Review
KW - Sample quality
UR - http://www.scopus.com/inward/record.url?scp=84948776147&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948776147&partnerID=8YFLogxK
M3 - Article
C2 - 26543078
AN - SCOPUS:84948776147
VL - 12
SP - 291
EP - 300
JO - Cancer Genomics and Proteomics
JF - Cancer Genomics and Proteomics
SN - 1109-6535
IS - 6
ER -