Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G

Una S. Ryan, Duane R. Schultz, Peter J. Del Vecchio, James W. Ryan

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.

Original languageEnglish (US)
Pages (from-to)748-749
Number of pages2
JournalScience
Volume208
Issue number4445
DOIs
StatePublished - 1980

ASJC Scopus subject areas

  • General

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