Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G

Una S. Ryan; Duane R. Schultz; Peter J. Del Vecchio; James W. Ryan

doi:10.1126/science.7367890

Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G

Una S. Ryan, Duane R. Schultz, Peter J. Del Vecchio, James W. Ryan

Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.

Original language	English (US)
Pages (from-to)	748-749
Number of pages	2
Journal	Science
Volume	208
Issue number	4445
DOIs	https://doi.org/10.1126/science.7367890
State	Published - 1980

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title = "Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G",

abstract = "Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.",

author = "Ryan, {Una S.} and Schultz, {Duane R.} and {Del Vecchio}, {Peter J.} and Ryan, {James W.}",

year = "1980",

doi = "10.1126/science.7367890",

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T1 - Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G

AU - Ryan, Una S.

AU - Schultz, Duane R.

AU - Del Vecchio, Peter J.

AU - Ryan, James W.

PY - 1980

Y1 - 1980

N2 - Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.

AB - Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.

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JF - Science

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Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G

Abstract

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