Endophthalmitis outbreaks following cataract surgery: Causative organisms, etiologies, and visual acuity outcomes

Avinash Pathengay, Harry W Flynn, Ryan F. Isom, Darlene Miller

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A systematic review of 27 reports of endophthalmitis outbreaks following cataract surgery between 1985 and 2011 found the 2 most common causes associated with the outbreaks were contaminated solutions, 10 reports (37%), and contaminated phacoemulsification machines, 6 reports (22.2%). Other possible sources of contamination included ventilation systems, 3 (11.1%); defective sterilization, 3 (11.1%); miscellaneous, 3 (11.1%); in 5 outbreaks (18.5%), no possible source could be identified. Bacteria occurred in 23 outbreaks (85.2%) and fungus in 4 (14.8%). Causative organisms were gram-negative bacteria, 15 (65.2%); gram-positive bacteria, 5 (21.7%); and both gram-positive and gram-negative bacteria, 3 (13.1%). Pseudomonas aeruginosa was causative in 14 of 27 (51.8%) gram-negative bacteria. After treatment in 229 patients, a visual acuity outcome of 20/400 or better was achieved in 127 patients (55.5%). Outbreaks of endophthalmitis following cataract surgery are often caused by gram-negative organisms and can be associated with poor visual outcomes. In this review, the most common source was irrigation solutions used perioperatively.

Original languageEnglish
Pages (from-to)1278-1282
Number of pages5
JournalJournal of Cataract and Refractive Surgery
Volume38
Issue number7
DOIs
StatePublished - Jul 1 2012

Fingerprint

Endophthalmitis
Cataract
Visual Acuity
Disease Outbreaks
Gram-Negative Bacteria
Phacoemulsification
Gram-Positive Bacteria
Pseudomonas aeruginosa
Ventilation
Fungi
Bacteria

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Surgery

Cite this

Endophthalmitis outbreaks following cataract surgery : Causative organisms, etiologies, and visual acuity outcomes. / Pathengay, Avinash; Flynn, Harry W; Isom, Ryan F.; Miller, Darlene.

In: Journal of Cataract and Refractive Surgery, Vol. 38, No. 7, 01.07.2012, p. 1278-1282.

Research output: Contribution to journalArticle

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