Endophthalmitis caused by Klebsiella species

Jayanth Sridhar, Harry W Flynn, Ajay Kuriyan, Sander Dubovy, Darlene Miller

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

PURPOSE:: To report the clinical presentation, antibiotic sensitivities, treatment strategies, and visual outcomes associated with endophthalmitis caused by Klebsiella species. METHODS:: A noncomparative consecutive case series. Microbiology database records were retrospectively reviewed for all patients with endophthalmitis caused by Klebsiella species from 1990 to 2012 at a large university referral center. The corresponding clinical records were then reviewed to evaluate the endophthalmitis clinical features and treatment outcomes. RESULTS:: Seven patients were identified. Clinical settings included endogenous (n = 3), posttraumatic (n = 2), trabeculectomy bleb-associated (n = 1), and postpenetrating keratoplasty (n = 1). Five patients presented with hypopyon. Presenting visual acuity ranged from 20/60 to light perception in nonendogenous cases and 1/200 to light perception in endogenous cases. Klebsiella was sensitive to aminoglycosides, third-generation cephalosporins, and second- and third-generation fluoroquinolones in all cases. Initial treatment strategies were vitreous tap and injection (n = 4), pars plana vitrectomy with intravitreal antibiotics (n = 2), and anterior chamber tap and injection (n = 1). All three endogenous cases later underwent enucleation or evisceration. In nonendogenous cases, the final visual acuity was 20/70 or better in all 4 patients. CONCLUSION:: Endophthalmitis caused by Klebsiella species is associated with poor visual outcomes. Endogenous cases had high rates of enucleation or evisceration.

Original languageEnglish
Pages (from-to)1875-1881
Number of pages7
JournalRetina
Volume34
Issue number9
DOIs
StatePublished - Jan 1 2014

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Endophthalmitis
Klebsiella
Visual Acuity
Anti-Bacterial Agents
Light
Injections
Trabeculectomy
Corneal Transplantation
Temazepam
Fluoroquinolones
Vitrectomy
Anterior Chamber
Aminoglycosides
Cephalosporins
Blister
Microbiology
Referral and Consultation
Databases
Therapeutics

Keywords

  • Bacterial eye infections
  • Endogenous
  • Endophthalmitis
  • Klebsiella

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Endophthalmitis caused by Klebsiella species. / Sridhar, Jayanth; Flynn, Harry W; Kuriyan, Ajay; Dubovy, Sander; Miller, Darlene.

In: Retina, Vol. 34, No. 9, 01.01.2014, p. 1875-1881.

Research output: Contribution to journalArticle

Sridhar, Jayanth ; Flynn, Harry W ; Kuriyan, Ajay ; Dubovy, Sander ; Miller, Darlene. / Endophthalmitis caused by Klebsiella species. In: Retina. 2014 ; Vol. 34, No. 9. pp. 1875-1881.
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