Endophthalmitis caused by gram-negative organisms

W. D. Irvine, Harry W Flynn, Darlene Miller, S. C. Pflugfelder

Research output: Contribution to journalArticle

135 Citations (Scopus)

Abstract

The medical records of 52 patients (53 eyes) with culture-proven gram- negative endophthalmitis between January 1982 and December 1990 were reviewed. Pseudomonas aeruginosa (23% [12/53]) and Haemophilus influenzae (19% [10/53]) were the most frequent isolates in this series. Overall, 26 (49%) of 53 treated patients achieved 20/400 or better visual acuity. Fifty- two (98%) of the original 53 gram-negative isolates were sensitive to the aminoglycoside antibiotics. To determine their sensitivity to recently developed antibiotics, 35 of the isolates were again grown on culture media and their sensitivities to ceftazidime, ciprofloxacin, and imipenem were obtained. Only ceftazidime demonstrated in vitro efficacy for all the organisms tested.

Original languageEnglish
Pages (from-to)1450-1454
Number of pages5
JournalArchives of Ophthalmology
Volume110
Issue number10
StatePublished - Oct 21 1992

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Endophthalmitis
Ceftazidime
Anti-Bacterial Agents
Imipenem
Haemophilus influenzae
Aminoglycosides
Ciprofloxacin
Pseudomonas aeruginosa
Visual Acuity
Medical Records
Culture Media
In Vitro Techniques

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Irvine, W. D., Flynn, H. W., Miller, D., & Pflugfelder, S. C. (1992). Endophthalmitis caused by gram-negative organisms. Archives of Ophthalmology, 110(10), 1450-1454.

Endophthalmitis caused by gram-negative organisms. / Irvine, W. D.; Flynn, Harry W; Miller, Darlene; Pflugfelder, S. C.

In: Archives of Ophthalmology, Vol. 110, No. 10, 21.10.1992, p. 1450-1454.

Research output: Contribution to journalArticle

Irvine, WD, Flynn, HW, Miller, D & Pflugfelder, SC 1992, 'Endophthalmitis caused by gram-negative organisms', Archives of Ophthalmology, vol. 110, no. 10, pp. 1450-1454.
Irvine, W. D. ; Flynn, Harry W ; Miller, Darlene ; Pflugfelder, S. C. / Endophthalmitis caused by gram-negative organisms. In: Archives of Ophthalmology. 1992 ; Vol. 110, No. 10. pp. 1450-1454.
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